Know Cancer

or
forgot password

Long-Acting Lanreotide as a Volume Reducing Treatment of Polycystic Livers


Phase 2/Phase 3
18 Years
88 Years
Not Enrolling
Both
Polycystic Liver Disease, Hepatomegaly, Liver Diseases, Polycystic Kidney, Autosomal Dominant

Thank you

Trial Information

Long-Acting Lanreotide as a Volume Reducing Treatment of Polycystic Livers


Inclusion Criteria:



- 18 yrs-of age

- Multiple cysts > 20

- Cooperating patient

- Is willing and able to comply with the study drug regimen and all other study
requirements

- Willingness to give written informed consent

Exclusion Criteria:

- Use of oral anticonceptives or estrogen suppletion

- Females who are pregnant or breast-feeding

- History or other evidence of chronic pulmonary disease associated with functional
limitation

- History of severe cardiac disease

- History or other evidence of severe illness or any other conditions which would make
the patient, in the opinion of the investigator, unsuitable for the study

- Symptomatic gallstones

- Renal failure requiring hemodialysis

Type of Study:

Interventional

Study Design:

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Outcome Measure:

Reduction of total liver volume as determined by CT scan

Outcome Time Frame:

6 months

Principal Investigator

Joost PH Drenth, MD, PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Radboud University Medical Center Nijmegen

Authority:

Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)

Study ID:

CMO 2007/010;ABR NL16194.091.0

NCT ID:

NCT00565097

Start Date:

October 2007

Completion Date:

Related Keywords:

  • Polycystic Liver Disease
  • Hepatomegaly
  • Liver Diseases
  • Polycystic Kidney, Autosomal Dominant
  • Polycystic Liver Disease
  • Autosomal Dominant Polycystic Kidney Disease
  • Liver cyst
  • Lanreotide
  • Hepatomegaly
  • Polycystic Kidney Diseases
  • Liver Diseases
  • Polycystic Kidney, Autosomal Dominant
  • Cysts

Name

Location