Metabolic Syndrome in PCOS: Precursors and Interventions
Once enrolled in the study, you will have a physical exam done. This includes getting a
medical history, height, weight, blood pressure and heart rate. We will also listen to your
heart and lungs. We will also look at your skin and determine what stage of puberty you are
in by looking at your breast growth and body hair. You will also have two (maybe three)
blood tests. The first one is an oral glucose tolerance test (OGTT). During this test, we
will have you drink an orange sugary drink and then we will draw your blood. The second
test is a frequently sampled intravenous glucose tolerance test (FSIGT). During this test,
we will give you insulin through one IV catheter and then we will draw blood from another IV
catheter. The third test that you might have done is an ACTH test. During this test, we
will draw your blood and then you will be given a dose of cortrosyn (a hormone that your
body already makes) and then we will draw your blood again. You will also have two scans of
your body done during your visit. There will be a Dual Energy X-Ray Scan (DEXA) and a
Magnetic Resonance Imaging Scan (MRI). You will be placed in the machines and then the
scanner will move over your body.
Observational
Observational Model: Family-Based, Time Perspective: Prospective
It is believed that PCOS is inherited. We are trying to look for clinical, blood and/or genetic markers of PCOS in the sisters and daughters of women with PCOS
age 8 until onset of menses
No
Andrea Dunaif, MD
Principal Investigator
Northwestern University-Chicago, Il.
United States: Institutional Review Board
0956-023
NCT00559390
July 2006
October 2012
Name | Location |
---|---|
Northwestern University | Chicago, Illinois 60611 |