The Effect of Primary Surgical Treatment on Survival in Patients With Metastatic Breast Cancer at Diagnosis
This is a randomised, controled clinical trial. Our aim is to observe whether primary
surgery improves survival in metastatic breast cancer. Women who have metastatic breast
cancer at the initial diagnosis will be included in the study. There will be two study arms:
primary surgery and systemic chemotherapy groups.
In the primary surgery group patients will have adjuvant therapies after they had the proper
surgery. In the systemic chemotherapy group patients will be followed after their initial
therapy and will have surgery only if they have locoregional problems (such as wide necrosis
or bleeding, etc). During the follow-up period, patients will be seen in every 6 months.
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Measure: all cause mortality
Atilla Soran, MD, MPH
University of Pittsburgh
Turkey: Ministry of Health