Assessment of the Utility of CT Follow Up in the Long Term Follow Up of Patients With Metastatic Non Seminomatous Germ Cell Tumour (NSGCT)
- To assess the frequency of relapse or recurrent abnormalities detected by CT scan in
patients on long-term follow-up for metastatic nonseminomatous germ cell tumour
- To assess the utility of CT scan-assessment in these patients.
- To assess the prognostic factors predictive of late relapse in NSGCT.
OUTLINE: This is a multicenter study.
Patients are screened by CT scan of the chest, abdomen, and pelvis for detectable
abnormalities or indications of late relapse. Scans are classified as positive or negative,
according to standard CT criteria, by a radiologist with expertise in testicular cancer
imaging. Patients with negative scans are followed yearly by clinical examination and tumor
marker assessment, and every 5 years by CT imaging. Additional follow-up is performed at the
discretion of the attending physician. Patients with positive scans undergo confirmation of
relapse, whenever possible, by surgical excision or biopsy and treatment is initiated
according to best clinical practice. If the follow-up scan is equivocal, patients are
advised to have a follow-up scan of the affected region in 6 months.
Rate of abnormalities due to nonseminomatous germ cell tumour (NSGCT) detected on initial CT-scan
Robert A. Huddart, MD
Royal Marsden NHS Foundation Trust