Know Cancer

forgot password

Pulmonary Function at Presentation and Follow-up in Hemato-Oncology 3-7 Years

3 Years
7 Years
Not Enrolling
Acute Lymphoblastic Leukemia, Acute Myeloblastic Leukemia, Solid Tumors,, Hodgkin's Disease, Non-Malignant

Thank you

Trial Information

Pulmonary Function at Presentation and Follow-up in Hemato-Oncology 3-7 Years

Pulmonary function tests (PFTs) are a part of the routine follow-up of patients receiving
anti-cancer treatment. Treatment is frequently associated with diverse pulmonary damage
which may become functionally and clinically evident many years later. PFTs may help to
quantify the damage in the lungs; help to evaluate the point at which lung function deviates
from normal to allow early intervention before irreversible lung damage occurs and thereby
to reduce morbidity and mortality.

Reliable PFTs in the preschool age have traditionally been difficult to perform, but recent
publications have demonstrated that the majority of preschool children can produce
reproducible forced expiratory flow volume (FEVC) curves with proper coaching techniques.
This recent development may enable studying the long term effect (years) of treatment on
lung function in young children suffering from hemato-oncologic diseases.

Inclusion Criteria:

- All pediatric patients (age 3-7 years) with hemato-onclogic diseases that were
treated at the Hemato-Oncology Department, and were sent to the pediatric pulmonary

Type of Study:


Study Design:

Observational Model: Cohort, Time Perspective: Retrospective

Principal Investigator

Ori Efrati, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Sheba Medical Center


Israel: Israeli Health Ministry Pharmaceutical Administration

Study ID:




Start Date:

October 2005

Completion Date:

October 2006

Related Keywords:

  • Acute Lymphoblastic Leukemia
  • Acute Myeloblastic Leukemia
  • Solid Tumors,
  • Hodgkin's Disease
  • Non-Malignant
  • acute lymphoblastic leukemia
  • long-term lung function
  • Hodgkin Disease
  • Leukemia
  • Leukemia, Lymphoid
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Leukemia, Myeloid, Acute
  • Leukemia, Myeloid