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Acupuncture for Mucositis Pain in Cancer Care

18 Years
70 Years
Not Enrolling
Mucositis, Pain, Leukemia

Thank you

Trial Information

Acupuncture for Mucositis Pain in Cancer Care

Acupuncture is one of the oldest, most commonly used medical procedures in the world. The
practice originated in China more than 2,000 years ago, and is widely used by doctors in
Korea, China, Japan, and other countries to ease pain or various symptoms. In the past two
decades, acupuncture has grown in popularity in the United States, and by 2002, an estimated
8.2 million adults in the US report having used acupuncture.

The term acupuncture describes a family of procedures involving stimulation of anatomical
points on the body by a variety of techniques. The acupuncture technique that has been most
studied scientifically involves penetrating the skin with thin, solid, metallic needles that
are manipulated by the hands or by electrical stimulation. Acupuncture needles are
metallic, solid, and hair-thin. People experience acupuncture differently, but most feel no
or minimal pain as the needles are inserted. Some people are energized by treatment, while
others feel relaxed.

Acupuncture has been used to ease some cancer treatment-related side effects such as nausea
and vomiting. In this study we will assess the potential usefulness of acupuncture to ease
the pain associated with mucositis.

Inclusion Criteria:

- Newly diagnosed with leukemia (such as acute myelogenous leukemia) and receiving
chemotherapy for induction, consolidation or re-induction or high dose preparative
regimen for bone marrow transplantation in the Johns Hopkins Oncology Inpatient

- Participation in standard leukemia-treatment regimens

- Expectation of survival of three weeks for completion of the study

Exclusion Criteria:

- Acupuncture treatment within the previous 6 weeks

- Unable to achieve platelet count of at least 10,000 with platelet support

- Radiation therapy within one month of enrollment

- Pregnant women

- History of substance abuse, including alcohol and IV drug users

Type of Study:


Study Design:

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Supportive Care

Principal Investigator

Adrian S Dobs, MD MHS

Investigator Role:

Principal Investigator

Investigator Affiliation:

Johns Hopkins University


United States: Institutional Review Board

Study ID:




Start Date:

Completion Date:

Related Keywords:

  • Mucositis
  • Pain
  • Leukemia
  • mucositis pain
  • cancer
  • pain
  • acupuncture
  • mucositis
  • cancer pain
  • Leukemia
  • Mucositis



Johns Hopkins Medical Institutions Baltimore, Maryland  21205