Descriptive Study Evaluating the Presence and Function of Natural Killer Cells in Elderly Patients With Acute Myeloid Leukemia in First Remission.
OBJECTIVES:
Primary
- Determine the evolution of functional receptors of natural killer (NK) cells after
completion of chemotherapy in elderly patients with acute myeloid leukemia in first
remission.
Secondary
- Measure the kinetics of cytotoxic functional recovery of NK cells.
- Determine activation markers of NK cells.
OUTLINE: This is a multicenter study.
Patients receive 1 course of consolidation therapy comprising an anthracycline and
cytarabine to induce first remission.
Blood is collected on day 0 of the consolidation course and then every 2 weeks for 8 weeks.
Interventional
Masking: Open Label, Primary Purpose: Treatment
Evolution of functional natural killer (NK) cells after chemotherapy
No
Norbert Vey, MD
Institut Paoli-Calmettes
United States: Federal Government
CDR0000564106
NCT00540956
November 2006
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