Know Cancer

or
forgot password

Optical Sensor for Photodynamic Detection of Oral Pathology


N/A
18 Years
75 Years
Open (Enrolling by invite only)
Both
Mouth Diseases

Thank you

Trial Information

Optical Sensor for Photodynamic Detection of Oral Pathology


This study determined the change in the optical properties of oral tissues, and combine
these with conventional semiquantitative histopathological to have information of the oral
pathology.

The study to determine the absorption and reflection spectra of healthy and pathological
oral tissues and to correlate these with oral pathology. Rationale is that tissue
architecture, components, metabolic processes and vasculature change with the onset and
progression of pathology. Each of these factors has optical signatures that detected
non-invasively.

A soft small fiberoptic pen shape sensor with fiberoptic-based spectrographic system place
in selective oral cavity. Six measurements and image will be taking within approximate 5
minutes.

The possible risks and/or discomforts associated with the procedures described in this study
include some discomfort of having the optical tool placed in the mouth the device will be
removed immediately. There may also be risks to participating that are currently
unforeseeable.

There are no direct benefit but potential benefit to society by helping to develop new tools
for early detection, monitoring, screening for oral pathology


Inclusion Criteria:



- Male or Female age 18 years and older

Exclusion Criteria:

- Age less than 18 years old

Type of Study:

Observational

Study Design:

Observational Model: Case-Only, Time Perspective: Prospective

Outcome Measure:

Optical Sensor for Photodynamic Detection of Oral Pathology

Outcome Time Frame:

up to 12 months

Safety Issue:

No

Principal Investigator

Petra Wilder-Smith, DDS,PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Beckman Laser Institute, University of Calfornia Irvine

Authority:

United States: Institutional Review Board

Study ID:

NIH-OCT-EB-093-07

NCT ID:

NCT00540774

Start Date:

April 2003

Completion Date:

July 2015

Related Keywords:

  • Mouth Diseases
  • oral cancer
  • oral mucositis
  • oral stomatitis
  • Mouth Diseases

Name

Location

Beckman Laser Institute, University of California IrvineIrvine, California  92612
UCI student health centerIrvine, California  92612