A Randomized Single Blind Controlled Trial of Beads vs. Doxorubicin Eluting Beads for Arterial Embolization of Hepatocellular Carcinoma (HCC)
Biocompatibles LC Bead (also known as DC Bead in Asia & Europe) microspheres are preformed
soft, deformable microspheres that may be loaded with doxorubicin and used to occlude blood
flow to a cancerous tumour. LC Bead microspheres consist of a macromere derived from PVA.
The fully polymerized microsphere is approximately 90% water and is compressible to
approximately 30% by diameter. The microspheres can be delivered through conventional
catheters (4-5Fr) or micro-catheters in the 2-3Fr range. These microspheres, like all agents
used for arterial embolization, are mixed with radiographic contrast prior to administration
in order to allow for fluoroscopic control of the embolization procedure.
Interventional
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
Response to treatment by RECIST criteria
2 to 3 weeks
No
Karen T Brown, MD
Principal Investigator
Memorial Sloan-Kettering Cancer Center
United States: Food and Drug Administration
07-099
NCT00539643
November 2007
February 2014
Name | Location |
---|---|
Memorial Sloan-Kettering Cancer Center 1275 York Avenue | New York, New York 10021 |