Konzentrationen Von Ertapenem in Kolorektalem Gewebe
The purpose of this study is to determine the tissue kinetics of ertapenem in colorectal
tissue from three hours up to six hours (25% of dosing interval) after administration of
ertapenem before an elective surgical intervention (open or laparoscopic surgery) at the
colon/rectum. Subjects are patients. Hospitalized patients 18 years or older requiring
elective surgical intervention (open or laparoscopic surgery) at the colon will be eligible
for this study.
Allocation: Non-Randomized, Endpoint Classification: Pharmacokinetics Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Concentration of ertapenem in colorectal tissue in mg/kg 3 to 6 hours after a single dose of 1 gram ertapenem I.V..
3 to 6 hours after a single dose of 1 gram ertapenem I.V..
Doris Henne-Bruns, Prof. Dr.
University of Ulm, Dept. of Visceral Surgery
Germany: Federal Institute for Drugs and Medical Devices