Trial Information

An Observation of the Change in Percent Lean Body Mass of Stage III Non-Small Cell Lung Cancer Undergoing Radiation Treatment

OBJECTIVES:

Primary

- To determine energy and protein consumption on an average radiotherapy treatment day
using the multiple pass method 24-hour analysis of food recall at baseline and
treatment end.

- To compare energy and protein by mouth intake from baseline to treatment end.

- To measure and compare diet quality from baseline to radiotherapy treatment end by
Healthy Eating Index (HEI) score.

- To determine lean body mass versus fat mass using a bioelectrical impedance analysis
machine.

- To compare body fat to lean body mass percentage at baseline with that at radiotherapy
treatment end.

- To correlate energy and protein consumption with lean body mass at baseline and
treatment end.

- To determine the change in appetite throughout radiotherapy by comparing data obtained
by interview at baseline and radiotherapy treatment end.

- To determine the change in performance level (Karnofsky percentage) associated with the
radiotherapy through a series of questions asked at baseline and treatment end.

OUTLINE: Patients receive radiotherapy as planned for 7 weeks. Patients undergo an interview
on treatment day 1 (before initiation of radiotherapy) and treatment day 35 (after
completion of radiotherapy) regarding recent food consumption history and appetite.
Patients' standing weight and height are measured on these days and their body composition,
measured with a bioelectrical impedance analysis (BIA) device, are also taken. Patients'
Karnofsky performance score are obtained from their medical record.