Partial Breast Irradiation for Patients Undergoing Breast Conservation Therapy for Early Stage Breast Cancer: A Pilot Study
- To determine the cosmetic outcome resulting from partial breast irradiation using two
- To determine patient satisfaction with partial breast irradiation as it pertains to
their overall treatment experience as measured by a questionnaire.
- To determine if there are patient factors that limit a patient's suitability to receive
partial breast irradiation delivered by a particular technique.
- To evaluate wound healing and overall complication rate after partial breast
- To determine ipsilateral breast tumor recurrence rates and tumor bed recurrence rates.
OUTLINE: Patients undergo partial breast irradiation comprising either MammoSite®
brachytherapy twice daily for 5-10 days OR 3-dimensional conformal radiotherapy twice daily
for 5-10 days.
After completion of study therapy, patients are followed periodically for up to 5 years.
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care
Cosmetic outcome as determined by an established scale employed by the radiation oncologist and the surgeon
1 month after RT & Q3mos for one year
Janice Lyons, MD
Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center
United States: Federal Government
|Lake/University Ireland Cancer Center||Mentor, Ohio 44060|
|Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center||Cleveland, Ohio 44106-5065|
|UHHS Chagrin Highlands Medical Center||Orange Villager, Ohio 44122|
|UHHS Westlake Medical Center||Westlaker, Ohio 44145|