A Multicenter Prospective Phase II Study Evaluating Peripheral Neurotoxicity by Using FACT-GOG/NTX Questionnaire in Patients With Ovarian Cancer in Relapse Treated by Paclitaxel +/- EPO. Validation of a French Version of This Questionnaire
Inclusion Criteria:
- Femal patient aged > 18 years
- Histologically proven diagnosis of cancer of the ovary, the fallopian tube or
peritoneal
- patients whose disease progresses or relapses
- patients having received at least a line of platinum-based chemotherapy
- patients whose treatment of relapse is envisaged to comprise paclitaxel
- patients who will receive EPO for treatment of their anaemia
- ECOG performans status < 2
- life expectancy > 16 weeks
- patient who has clearly given her consent by signing on informed consent form prior
to participation
Exclusion Criteria:
- peripheral neuropathy grade > 2
- history of ischemic cardiopathy, congestive heart failure (NYHA>2), arrhythmia,
hypertension or significant valvulopathy
- abnormal biological values
- A therapy or a serious disease which could involve a risk for the patient or
interfere with the aims of the study
- patient who is pregnant, breast feeding or using inadequate contraception
- concomitant therapy by a potentially neurotoxic drug
- concomitant inclusion in another therapeutic trial which could interfere with the
aims of the study
- patient who for familial, sociological, geographical or psychological condition could
not be followed correctly