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Newer Breast MRI Sequences for the Evaluation of Breast Cancer - Vibrant-DE and 3DFSE-XETA: Feasibility Evaluation


N/A
21 Years
N/A
Open (Enrolling)
Female
Breast Cancer

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Trial Information

Newer Breast MRI Sequences for the Evaluation of Breast Cancer - Vibrant-DE and 3DFSE-XETA: Feasibility Evaluation


OBJECTIVES:

Primary

- Evaluate the feasibility of two new pulse sequences for breast MRI using newly
developed software (volume imaging for breast assessment NT [VIBRANT-DE] and 3D fast
spin-echo extended echo-train acquisition [3DFSE-XETA]).

Secondary

- Assess the performance of two breast pulse sequences quantitatively and qualitatively,
and compare these results with the same parameters using standard breast MRI sequences.

OUTLINE: Conventional breast images will be taken using standard sequences consisting of
T2-weighted imaging and T1-weighted imaging before and after contrast (gadopentetate
dimeglumine); these will be used for the diagnostic examination. Following the diagnostic
examination, two additional sequences, volume imaging for breast assessment NT (VIBRANT-DE)
and 3D fast spin-echo extended echo-train acquisition (3DFSE-XETA), will be performed.

Inclusion Criteria


DISEASE CHARACTERISTICS:

- Undergoing a diagnostic breast MRI for a known or suspicious lesion

PATIENT CHARACTERISTICS:

- Female

- Not pregnant

- Able to comply with or complete the MRI exam

- No claustrophobia or high levels of anxiety

- No pacemaker, aneurysm clip, or any other condition that would warrant avoidance of a
strong magnetic field

- No other condition that would preclude MRI examination

PRIOR CONCURRENT THERAPY:

- Not specified

Type of Study:

Interventional

Study Design:

Masking: Open Label, Primary Purpose: Diagnostic

Outcome Measure:

Feasibility of two new pulse sequences

Safety Issue:

No

Principal Investigator

Elizabeth Morris

Investigator Role:

Principal Investigator

Investigator Affiliation:

Memorial Sloan-Kettering Cancer Center

Authority:

Unspecified

Study ID:

CDR0000560413

NCT ID:

NCT00514319

Start Date:

July 2007

Completion Date:

Related Keywords:

  • Breast Cancer
  • breast cancer
  • Breast Neoplasms

Name

Location

Memorial Sloan-Kettering Cancer CenterNew York, New York  10021