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Curbing Tobacco Use in Suburban and Rural Schools

Phase 1
14 Years
16 Years
Open (Enrolling)

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Trial Information

Curbing Tobacco Use in Suburban and Rural Schools

The proposed study will test the effectiveness of the Internet-based cigarette smoking and
spit tobacco (ST) prevention and cessation in-class curriculum for rural teens.
Supplemented by "cyber-support" (chat room and bulletin board), the intervention program
also will make use of a human social support environment (via trained school personnel, chat
rooms, bulletin boards). The study will use a nested cohort design in which high schools
are the unit of design, allocation, and analysis. Tenth-grade students (ages 14-16) within
each intervention school will receive a 7-week interactive, Internet-based tobacco
prevention and cessation curriculum. Using computerized surveys, study participants will be
evaluated at baseline, 6-month, 12-month, and 18-month follow-ups. The study has been
designed to permit analyses sensitive enough to detect differences for the two primary
hypotheses: reductions in smoking initiation and smoking cessation. Trends in ST use after
exposure to the intervention program will also be assessed. The design will also permit
analysis of stage-of-change dynamics and mediators for both acquisition and cessation of
both forms of tobacco.

Inclusion Criteria:

1. Subjects aged 14-16 years of age (9th and 10th-graders) who speak, read and write

2. Subjects are students from schools located in suburban and rural communities
approximately 200 miles from Houston.

3. Subjects with approved parental consent

Exclusion Criteria:

1) Disruptive individuals who are not able to work with the program

Type of Study:


Study Design:

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Outcome Measure:

Reductions in smoking initiation

Outcome Time Frame:

Baseline, 6-month, 12-month, and 18-month

Safety Issue:


Principal Investigator

Alex Prokhorov, MD, PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:

M.D. Anderson Cancer Center


United States: Institutional Review Board

Study ID:




Start Date:

July 2006

Completion Date:

Related Keywords:

  • Epidemiology
  • Epidemiology
  • Cancer Prevention
  • Smoking Cessation
  • Smoking Prevention
  • Focus Groups



UT MD Anderson Cancer Center Houston, Texas  77030