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Thyroid Nodules

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Trial Information

As opposed to widely investigated condition of cardiovascular system in patients with
functional disorders of thyroid gland, the relationship between thyroid hormones and
hemodynamic parameters in euthyroid patients remains not enough clear.

We detect the parameters of blood pressure and thyroid hormones in euthyroid patients with
thyroid nodules directly before planned operation on the thyroid gland.

As the study is carries out directly before operation, that assumes presence of preoperative
stress in patients, activity of the sympatho - adrenal system is estimated in addition.

On the one hand, the design of our research will allow to estimate relationship of thyroid
hormones with the parameters of blood pressure in conditions of euthyroidism, on the other
hand - to investigate features of blood pressure in patients with thyroid nodules.

The research of the patients in the preoperative period will enable to select the group of
patients without pathology of cardiovascular system whose increased blood pressure is
connected with preoperative stress, that in turn will allow to exclude influence of the
pathology of the cardiovascular system on studied correlation.

Inclusion Criteria:

- Euthyroid patients with thyroid nodules before operation on the thyroid gland

Exclusion Criteria:

- Hyperthyroidism

- Hypothyroidism

Type of Study:


Study Design:

Time Perspective: Prospective

Principal Investigator

Yuriy Alexandrov, Professor

Investigator Role:

Study Chair

Investigator Affiliation:

Yaroslavl State Medical Academy


Russia: Ethics Committee

Study ID:




Start Date:

Completion Date:

December 2007

Related Keywords:

  • Thyroid Nodules
  • thyroid nodules, blood pressure, thyroid hormones
  • Thyroid Diseases
  • Thyroid Nodule