Inclusion Criteria

Inclusion criteria:

- Patients with histologically confirmed solid tumors or non-Hodgkin's lymphoma with
progression on prior standard therapies.

- Eastern Cooperative Oncology Group (ECOG) performance status of ≤ 2

- Adequate kidney function and laboratory values

Exclusion criteria:

- Patients who have received chemotherapy, any investigational drug, undergone major
surgery, or received wide field radiotherapy less than 4 weeks ago

- Patients who had a heart attack or have unstable angina within past 6 months

- Heart disease including congestive heart failure and uncontrolled high blood pressure

- Liver disease, abnormal gastrointestinal (GI) function or ongoing diarrhea

- Use of any anti-cancer therapy, including radiation therapy, or certain drugs while
on study

- Female patients who are pregnant or breast feeding.

Other protocol inclusion/exclusion criteria may apply.