Feasibility, Safety, and Effect of an Exercise Program for Adolescents and Young Adults With Cancer
Patients who are staying at M.D. Anderson for inpatient chemotherapy treatment will take
part in this study.
Participants in this study will be asked to take part in either mild physical exercise by
themselves for 20 minutes a day, or group exercise sessions of moderate intensity once a
day. Each participant will be evaluated by a physical therapist before participation.
Exercise programs will be designed for each individual. Participants will be encouraged to
attend group sessions and continue the exercise program during the time they are
outpatients. Participants will also have the opportunity to work with a personal trainer.
The group exercise program takes from 45 minutes to one hour, and will be performed under
the guidance of certified physical therapists and a personal trainer in the Pedi-Dome
located on the ninth floor of the Alkek Tower of M.D. Anderson. Participants who are not
feeling well enough to come to the Pedi-Dome on a given day will have the opportunity to
exercise in their hospital rooms with a physical therapist or trainer for 20 minutes.
The exercises are designed to promote flexibility, endurance, and strength. They include
activities such as stretching, pilates-yoga, aerobics, step aerobic training, use of
stationery bikes, and the use of therapeutic exercise balls, cuff weights, and dumbbells.
The activities will be tailored to each individual's abilities and special needs.
The total length of participation in this study is three months. Participants will be asked
to exercise each day that they are an inpatient and well enough to participate.
Participants will be encouraged to continue exercise and participation in the exercise
program when they are outpatients, but it will not be required. Participants will fill out
short questionnaires and be evaluated for quality of life, fatigue, physical strength, and
medical and nutritional status four times: at the time of enrollment in the study, and at
one, two, and three months after enrollment. The questionnaires will take about 15 minutes
This is an investigational study. A total of 40 patients will take part in this study. All
will be enrolled at M.D. Anderson.
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Supportive Care
Exercise Participation Rate
Participation in exercise program as measured through group attendance examined from study entry to three months later. Exercise participation rate was examined across 4 timepoints corresponding to inpatient chemotherapy treatments, and calculated as number of those exercising in each period divided by total participants in that period.
Baseline to 3 months
Martha Askins, PhD
M.D. Anderson Cancer Center
United States: Institutional Review Board
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