Prevalence of Endometrial Abnormalities In Obese Women
Women in this study will be asked to complete three different parts of the study. All three
parts of the study will be done during one visit to the gynecology center. First, you will
be asked to complete a survey/questionnaire that will give researchers information on your
background, weight history, gynecologic, and medical history. You will be assisted by a
research nurse and completion of the questionnaire is expected take about 30 minutes.
Second, you will be asked to have a blood sample drawn. About 2 tablespoons of blood will
be drawn. This blood will be used to look at different hormone levels that may be related
to your risk of endometrial abnormalities.
Third, an endometrial biopsy will be performed by one of the doctors running the study.
This will require you to have a full pelvic exam (much like when you have a pap smear),
which will include looking at the cervix (mouth of the womb) and putting a small pipelle
(straw) into the womb to collect a tissue sample. This procedure is routinely done in the
office. You will not be required to take medications prior to the procedure and you will
not receive a prescription for pain medication once the procedure is complete.
Completion of all three parts of the study may take between one to two hours. You and your
physician will be notified of your endometrial biopsy results.
This is an investigational study. Up to 200 participants will be enrolled in this study.
All will be enrolled at MD Anderson.
Observational Model: Case-Only, Time Perspective: Prospective
Prevalence of Endometrial Abnormalities in Obese and Lean Women
Karen H. Lu, MD
M.D. Anderson Cancer Center
United States: Institutional Review Board
|UT MD Anderson Cancer Center||Houston, Texas 77030|