Inpatient Functional and Cognitive Assessment in Older Adults With Acute Myelogenous Leukemia
- Test the feasibility of pre-treatment, bedside assessment of functional and cognitive
status in older adults with newly diagnosed acute myeloid leukemia (AML).
- Obtain preliminary data regarding the predictive value of pre-treatment, bedside
assessment of functional and cognitive status on overall survival, length of
hospitalization and early death.
OUTLINE: This is a prospective study.
At baseline, patients complete questionnaires including the Vulnerable Elders Survey
(functional status), the Mini-Mental Status Exam (cognition), and the Center for
Epidemiologic Studies-Depression. Patients also undergo physical function testing via the
Short Physical Performance Battery and hand grip strength. Further information parameters
are obtained by periodic medical chart reviews.
Patients are followed every 3 months for up to 2 years.
Observational Model: Cohort, Time Perspective: Prospective
feasibility of administering a functional assessment in clinical situation
Assessment of physical and cognitive function via a set of physical and congnitive tests
72 hours of admission
Heidi D. Klepin, MD
Comprehensive Cancer Center of Wake Forest University
United States: Institutional Review Board
|Wake Forest University Comprehensive Cancer Center||Winston-Salem, North Carolina 27157-1096|