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Quantitation of Left Ventricular Ejection Fraction as Part of F-18 FDG Whole Body PET/CT Scans For Tumor Staging

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Trial Information

Quantitation of Left Ventricular Ejection Fraction as Part of F-18 FDG Whole Body PET/CT Scans For Tumor Staging

Your doctor has ordered a PET/CT scan and a NM scan on you for routine care. By agreeing to
take part in this study, you will go through both of these procedures as you normally would.

For both imaging exams, you will be lying on your back. Every effort will be made to make
you as comfortable as possible. For theNM cardiac scan, you will be hooked up to a heart
monitor that will take a picture every time your heart beats. Your heart will be imaged from
several different views. This exam will take about 30 minutes.

The PET/CT cardiac scan will be done after completion of your normally scheduled PET/CT
scan. For this scan, you will be hooked to a heart monitor that records the beats of your
heart. While this monitor is attached, you will be imaged with the PET/CT scanner. The
PET/CT cardiac scan will take about 10-15 minutes after your PET/CT exam is completed.

Both imaging exams will provide a number that corresponds to the percent of blood pushed out
of the left ventricle of your heart during a resting state.

Taking part in this study should add between 10-15 additional minutes to your PET/CT visit.
This is due to the additional cardiac imaging time.

This is an investigational study. A total of up to 50 patients will take part in this
study. All will be enrolled at UTMDACC.

Inclusion Criteria:

- Patients undergoing both FDG PET/CT scan and RNV within two weeks interval, whether
for initial staging, restaging or to evaluate response to therapy.

- Patients who would consent to an additional 10-15 minutes acquisition of the gated
images after completion of their FDG PET/CT study with the additional radiation

- Patients with regular heart rate.

Exclusion Criteria:

- Blood glucose level above 200 mg/dL.

- Irregular heart rate.

- An interval of less than 1 day between the FDG PET/CT scan and RNV.

Type of Study:


Study Design:

Observational Model: Case-Only, Time Perspective: Prospective

Outcome Measure:

To compare the results, called an ejection fraction, of PET/CT and NM cardiac scans of heart.

Outcome Time Frame:

5 Years

Safety Issue:


Principal Investigator

Isis W. Gayed, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

M.D. Anderson Cancer Center


United States: Institutional Review Board

Study ID:




Start Date:

September 2004

Completion Date:

March 2009

Related Keywords:

  • Advanced Cancers
  • Advanced Cancers
  • Cardiac Function
  • Nuclear Medicine Cardiac Scan
  • Positron Emission Tomography
  • Radionuclide Ventriculography
  • Ventricular Ejection Fraction
  • PET/CT
  • RNV
  • Neoplasms



U.T.M.D. Anderson Cancer Center Houston, Texas  77030