Assessment and Rehabilitation of Cognitive Impairments in Pediatric Survivors of Cancer
The purpose of this study is to help determine specific cognitive-behavioral and
neurobiologic impairments associated with chemotherapy treatments in children with cancer
and to assess the efficacy of a cognitive intervention program for improving cognitive
impairments in these children.
- 5 children with any type of cancer in the initial stages of chemotherapy and/or
- 10 children with any type of cancer who have completed chemotherapy and cranial
- Children with pre-cancer/pre-chemotherapy history of brain injury, neurological,
psychiatric, neurodevelopmental and/or learning disorders including attention deficit
hyperactivity disorder will be excluded.
- Participants will be excluded for MRI contraindications such as orthodontia and
- Non-English speaking participants will be excluded due to the unavailability at this
time of translated cognitive testing and MRI assessments.
Type of Study:
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Performance on neuropsychological testing and brain activation patterns measured by functional MRI
Outcome Time Frame:
United States: Institutional Review Board
- Squamous Cel
- Acute Lymphocytic Leukemia
- Cognition Disorders
|Stanford University School of Medicine||Stanford, California 94305-5317|