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Molecular Epidemiology of Lymphoma Patients

18 Years
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Trial Information

Molecular Epidemiology of Lymphoma Patients

This study will include individuals diagnosed with lymphoma and individuals with no history
of cancer. Half of the participants in this study will have lymphoma, and half will have no
history of cancer. Information from both groups will be compared to help researchers try to
learn which factors may lead to the development of lymphoma.

If you agree to take part in this study, you will be asked to complete a questionnaire at M.
D. Anderson. In this questionnaire, you will be asked about your demographics (such as your
age, sex, etc.), certain environmental exposures (such as pollution), your medical history,
family history, diet, and your past and present smoking and alcohol use habits. This
questionnaire should take about 50 minutes to complete.

You will also have about 2 ½ tablespoons of blood drawn for special tests. These tests will
look for any biologic factors (such as changes in your DNA) that may be linked to lymphoma.
You will not be informed of the results of any of the testing done with your blood samples.

Your participation will be over in this study once your blood has been drawn.

This is an investigational study. Up to 800 participants will take part in this study. All
will be enrolled at M. D. Anderson.

Inclusion Criteria:

1. Cases only: Newly diagnosed, previously untreated patients with lymphoma as the
primary cancer.

2. Age 18 years and older.

3. Willing to donate 30ml of blood.

4. Willing to complete a self-administered questionnaire.

5. Controls only: No prior cancer.

Exclusion Criteria:

1. Cases only: Prior history of cancer other than lymphoma.

2. Unable to speak or read English

Type of Study:


Study Design:

Observational Model: Case Control, Time Perspective: Prospective

Outcome Measure:

To identify biologic (such as genes) and lifestyle factors that may increase a person's risk of developing lymphoma.

Outcome Time Frame:

4 Years

Safety Issue:


Principal Investigator

Randa El-Zein, MD, PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:

M.D. Anderson Cancer Center


United States: Institutional Review Board

Study ID:




Start Date:

August 2006

Completion Date:

April 2008

Related Keywords:

  • Lymphoma
  • Lymphoma
  • Epidemiology
  • Lifestyle Factors
  • Questionnaire
  • Survey
  • Lymphoma