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Advanced Ovarian Cancer and Sexuality Phase 1

19 Years
65 Years
Not Enrolling
Ovarian Cancer, Sexual Function

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Trial Information

Advanced Ovarian Cancer and Sexuality Phase 1

Hypothesis 1a: Compared to baseline pre-treatment data, and to existing data for women with
early-stage gynaecologic cancer, rates of sexual difficulties will be significantly higher
and frequency of sexual intercourse will be significantly lower in women with advanced
ovarian cancer. We hypothesize that difficulties specifically in the domains of sexual
desire, sexual distress, and genital pain will be the most common types of sexual
dysfunction to characterize women with advanced ovarian cancer.

Hypothesis 1b: We hypothesize that the degree of sexual symptoms will be significantly
greater at 3 months and 10 months post-treatment than compared to pre-treatment, and that
sexual difficulties may be significantly greater at 3 months post-treatment than at
10-months post-treatment.

Hypothesis 1c: We hypothesize that degree of sexual difficulty and sexual distress will be
significantly correlated with (a) overall well-being; (b) depressive symptoms; and (c)
relationship satisfaction.

Hypothesis 1d: As an exploratory analysis, we will investigate the relationship of ovarian
cancer-related variables (i.e., type of treatment, duration of treatment, number of
medications), and demographic variables (i.e., age, relationship duration, education) on
each of the hypotheses in 1a - 1c.

Inclusion Criteria:

- Women with Advanced Ovarian Cancer (AOC) who have not received treatment yet, but who
are seeking treatment at the BC Cancer Agency.

- Women must be able to understand English enough to fill out the questionnaire

- Mastery of written English is required. No translation services will be available for
this study.

Exclusion Criteria:

- Anyone without an AOC diagnosis, who are not seeking treatment at BCCA, or who cannot
understand enough English to complete the questionnaires will be excluded.

- Those who do not have a mastery of written English are excluded.

Type of Study:


Study Design:

Observational Model: Cohort, Time Perspective: Retrospective

Principal Investigator

Lori A Brotto, PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:



Canada: Health Canada

Study ID:




Start Date:

May 2007

Completion Date:

August 2011

Related Keywords:

  • Ovarian Cancer
  • Sexual Function
  • Advanced Ovarian Cancer
  • Sexual Function
  • Ovarian Neoplasms