Advanced Ovarian Cancer and Sexuality Phase 1
Hypothesis 1a: Compared to baseline pre-treatment data, and to existing data for women with
early-stage gynaecologic cancer, rates of sexual difficulties will be significantly higher
and frequency of sexual intercourse will be significantly lower in women with advanced
ovarian cancer. We hypothesize that difficulties specifically in the domains of sexual
desire, sexual distress, and genital pain will be the most common types of sexual
dysfunction to characterize women with advanced ovarian cancer.
Hypothesis 1b: We hypothesize that the degree of sexual symptoms will be significantly
greater at 3 months and 10 months post-treatment than compared to pre-treatment, and that
sexual difficulties may be significantly greater at 3 months post-treatment than at
10-months post-treatment.
Hypothesis 1c: We hypothesize that degree of sexual difficulty and sexual distress will be
significantly correlated with (a) overall well-being; (b) depressive symptoms; and (c)
relationship satisfaction.
Hypothesis 1d: As an exploratory analysis, we will investigate the relationship of ovarian
cancer-related variables (i.e., type of treatment, duration of treatment, number of
medications), and demographic variables (i.e., age, relationship duration, education) on
each of the hypotheses in 1a - 1c.
Observational
Observational Model: Cohort, Time Perspective: Retrospective
Lori A Brotto, PhD
Principal Investigator
UBC
Canada: Health Canada
H06-03235
NCT00488202
May 2007
August 2011
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