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African American Families and Lung Cancer Study


N/A
18 Years
N/A
Not Enrolling
Both
Lung Cancer

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Trial Information

African American Families and Lung Cancer Study


The purpose of the African American (AA) Families and Lung Cancer Study is to learn more
about (1) the beliefs of family members of AA patients with lung cancer about why AA get
lung cancer and (2) whether these beliefs are associated with their interest in genetic
testing for lung cancer risk and willingness to participate in clinical genetics research.
We plan to recruit 200 AAs (n = 100 current smokers and n = 100 never smokers) who are
considered to be as close as family (both biological and non-biological kin) to patients
with lung cancer who self-identify as AA (n = 115). Patients will be recruited from
Washington Cancer Institute at the Washington Hospital Center in Washington, DC. Family
members who self-identify as AA and are between the ages 18 and 55 will be eligible for the
study. A Washington Hospital Center recruiter will approach patients and ask their
willingness to be contacted for a telephone survey about their general well-being. As part
of the survey, patients will be asked to enumerate family and friends who they consider to
be as close as family, and asked to specifically focus on those who are current cigarette
smokers and those who have never smoked. Patients will be asked to give permission to
contact some or all of those enumerated. These family members will be mailed a letter to
inform them that unless they call to decline they will be contacted by a telephone
interviewer. The survey will include questions to assess family members' explanations for
the causes of lung cancer and reactions to possible explanations for disparities in lung
cancer between AA and Caucasian Americans (CA), perceived personal risk and worry about
developing lung cancer, smoking history, motivation to quit smoking, emotional responses to
the patient's diagnosis, racial identity, experience with racial discrimination, pros and
cons of genetic testing, and interest in genetic testing (the primary outcome variable).
Data analysis using hierarchical linear modeling will assess whether patient characteristics
and family members' endorsement of genetics as the cause of lung cancer are associated with
their interest in genetic testing and participation in clinical genetics research.

Inclusion Criteria


- INCLUSION CRITERIA:

Patients:

In order to be included in this study, patients with lung cancer must meet inclusion
criteria at 2 steps: (1) initial screening and written consent to be contacted by
telephone, and (2) provision of verbal consent at the time of telephone contact to
complete the survey.

Step 1a: In order to be approached about the study, patients must be (1) at least 18 years
of age, (2) diagnosed with lung cancer at any stage (Stages Ia-IV), (3) approved for
contact by their oncologist, and (4) identified by the recruiter or identified in medical
records as Black.

Step 1b: In order to provide consent for contact for the telephone survey, patients must
self-identify as AA/Black and must have been born in the U.S. Also, patients must be
willing to give permission to contact at least one family member or friend considered as
close as family who is a current cigarette smoker between the ages of 18 and 55 in order
to provide consent.

Step 2: At the point of the patient survey, all patients will be asked their
race/ethnicity. All patients who self-identify as AA/Black as defined by this research
will be administered the patient survey.

Family:

Family members must self-identify as AA and be between the ages of 18 and 55 to be
eligible for the study. Family also must meet the following inclusion criteria to be
classified as either a current smoker (defined below) or a never smoker (defined below).
These criteria for current smoker and never smoker are based on standard criteria used in
smoking research.

Current Smoker: to be included as a smoker , the family member must report having smoked
at least 100 cigarettes in their lifetime, and smoked 7 or more cigarettes in the past 7
days at the time of the family member survey.

Never Smokers: to be included as a never smoker , a family member must report no to
having smoked at least 100 cigarettes in their lifetime.

EXCLUSION CRITERIA:

Former smokers (i.e., family who have smoked at least 100 cigarettes in their lifetime but
smoked fewer than 7 cigarettes in the past 7 days) because previous research shows
consistently that these individuals hold attitudes and beliefs more similar to those of
current smokers than never smokers.

Patients who describe themselves as AA or Black but were not born in the U.S. will be
excluded from participation.

Type of Study:

Observational

Study Design:

Time Perspective: Prospective

Authority:

United States: Federal Government

Study ID:

999907161

NCT ID:

NCT00487760

Start Date:

June 2007

Completion Date:

August 2011

Related Keywords:

  • Lung Cancer
  • Lung Cancer
  • African-American Families
  • Genetic Risk Communication
  • Interest in Genetic Testing and Genetics Research
  • Health Disparities
  • Smoking Cessation
  • Lung Neoplasms

Name

Location

Washington Hospital Center Washington, District of Columbia  20010