Know Cancer

forgot password

Social Anxiety and Avoidance in Head and Neck Cancer Patients

21 Years
70 Years
Not Enrolling
Anxiety Disorder, Head and Neck Cancer, Lung Cancer

Thank you

Trial Information

Social Anxiety and Avoidance in Head and Neck Cancer Patients


- Determine the relationship between treatment-provoked social anxiety and avoidance in
patients previously treated for head and neck cancer.

- Determine the relationship between pre-cancer psychiatric diagnosis and post-treatment
social anxiety and avoidance in these patients.

- Determine the effect of social anxiety and/or avoidance on the quality of life of these

- Investigate the specificity of these relationships in patients with head and neck
cancer by comparing patients with head and neck cancer to patients with lung cancer.

OUTLINE: This is a cross-sectional study. Patients are stratified according to prior
treatment type (significantly impairing [surgery] vs less impairing

Patients undergo a face-to-face interview with a mental health clinician over 2 hours.
Patients complete multiple psychiatric/psychological assessments during the interview,
including the Structured Clinical Interview for DSM-IV (SCID); the Liebowitz Social Anxiety
Scale (SAS); the Performance Status Scale for Head and Neck Cancer Patients (PSS-HN); the
Social Phobia and Anxiety Inventory (SPAI); the State-Trait Anxiety Inventory (STAI);
Response to Stress Questionnaire, Cancer Version (RSQ-CV); the Functional Assessment of
Cancer Therapy (FACT-HNC (head neck cancer) or LC); the Voice Handicap Index (VHI); and the
Body Image Scale (BIS).

Cancer treatment and medical history information are gathered from patients' medical

Inclusion Criteria


- Diagnosis of 1 of the following:

- Head and neck cancer

- Lung cancer (control group)

- Must have received treatment for head and neck cancer or lung cancer within the past
5 years


- Able to speak and read English to answer surveys, interviews, and questionnaires


- See Disease Characteristics

Type of Study:


Study Design:

Observational Model: Case Control, Time Perspective: Prospective

Outcome Measure:

Level of social anxiety and avoidance in HNC patients post-treatment

Outcome Description:

Measured by the Liebowitz Social Anxiety Scale and the Social Phobia and Anxiety Inventory, containing 24 items with each item separately rated for fear as 0 (none), 1 (mild), 2 (moderate) to 3 (severe)and for avoidance behavior as 0 (never), 1 (occasionally), 2 (often), to 3 (usually). Scores are summed with lower values indicating lower levels of social anxiety and avoidance.

Outcome Time Frame:

at study entry, day 1

Safety Issue:


Principal Investigator

Kirsten Haman, PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Vanderbilt-Ingram Cancer Center


United States: Federal Government

Study ID:

VICC HN 0397



Start Date:

November 2003

Completion Date:

January 2008

Related Keywords:

  • Anxiety Disorder
  • Head and Neck Cancer
  • Lung Cancer
  • anxiety disorder
  • long-term effects secondary to cancer therapy in adults
  • head and neck cancer
  • non-small cell lung cancer
  • small cell lung cancer
  • Anxiety Disorders
  • Head and Neck Neoplasms
  • Lung Neoplasms



Vanderbilt-Ingram Cancer Center Nashville, Tennessee  37232-6838
MBCCOP - Meharry Medical College - Nashville Nashville, Tennessee  37208-3599