Patients with uncontrolled cancer pain despite treatment of oral morphine equivalent ≥100
mg/d will be randomly assigned to oral opioids to transdermal fentanyl (rotation group) or
oral oxycodone plus fentanyl (combination group). Patients answer a questionnaire that
included pain severity (0 to 10) and interference items at baseline and after one week.
Primary outcomes are change in pain score and treatment success.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care
Change in pain score and treatment success
Se Hoon Park, MD
Gachon University Gil Medical Center, Incheon, Korea
Korea: Food and Drug Administration