Trial Information

Research Participation: Decision Making and Outcomes in Cancer Clinical Trials

OBJECTIVES:

- Determine the relationship between disease factors, patient factors, and understanding
of the cancer clinical trial, and preferences for decision control in the decision to
participate in a cancer clinical trial by patients with stage II-IV pancreatic cancer
or stage III-IV colon or rectal cancer.

- Determine the relationship between disease factors, patient factors, understanding of
the cancer clinical trial, and preferences for decision control with satisfaction with
the decision to participate in a cancer clinical trial.

- Determine how quality of life, trust, and hope impact the decision to participate in a
cancer clinical trial and the satisfaction with this decision.

OUTLINE: This is a cross-sectional study.

Patients complete 12 questionnaires to assess their symptom burden (e.g., nausea, pain,
fatigue), sociodemographics, hope, quality of life, trust in the healthcare system, trust in
health professionals, research decision control, perceived risks, adequacy of research
information, clinical trial participation, and decision satisfaction.

PROJECTED ACCRUAL: A total of 200 patients will be accrued for this study.