Effect of Yoga on Weight and Fatigue in Breast Cancer Patients Study
21 Years
75 Years
Female
Breast Cancer
Trial Information
Effect of Yoga on Weight and Fatigue in Breast Cancer Patients Study
Women who are overweight or obese have a higher risk of breast cancer than normal weight
women. Furthermore, women who are overweight or obese or gain weight after diagnosis have an
increased risk of recurrence or dying from breast cancer compared with normal weight women.
Yoga has been associated with reduced weight gain and weight loss in persons without cancer.
However, no studies have tested whether yoga leads to less weight gain or weight loss in
breast cancer patients. Both obesity and the sequelae of breast cancer therapy can result in
reduced health-related quality of life and severe fatigue, which may also be favorably
affected by yoga practice. The specific aims of the proposed trial are to examine, in women
with Stage 0-IIIa breast cancer who are at least 3 months post primary treatment for their
disease (other than tamoxifen or aromatase inhibitors), the effects of a 6-month yoga
intervention on health-related quality of life, fatigue, and body weight.
Inclusion Criteria:
- Female
- Age 21-75
- Diagnosed with a primary breast cancer Stage 0-IIIa
- Current tamoxifen or aromatase inhibitor use is allowed
- At least 3 months post treatment (e.g., surgery, chemotherapy, or radiation therapy)
- BMI: 24 kg/m2 or greater (If Asian or Asian-American BMI: 23 kg/m2 or greater)
- No contraindications to participating in a yoga program
- Able to come for clinic visits, and attend weekly classes, and fill out
questionnaires and logs in English
- Gives informed consent, agrees to be randomly assigned
Exclusion Criteria:
- Plans to leave the study area within the follow-up period
- Is pregnant or plans to become pregnant during the study period.
- History of myocardial infarction (heart attack) or stroke in the previous 6 months,
or diabetes (current diagnosis)
- Has practiced yoga more than 1 time per month in the past six months.
- Current use of medications likely to interfere with adherence to interventions or
study outcomes
- Alcohol or drug abuse, significant mental illness (as assessed by study staff
impression)
Type of Study:
Interventional
Study Design:
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care
Outcome Measure:
quality of life, fatigue, and body weight
Outcome Time Frame:
baseline, 6 months, 12 months
Safety Issue:
No
Principal Investigator
Alyson Littman, PhD
Investigator Role:
Study Director
Investigator Affiliation:
Department of Epidemiology, UW
Authority:
United States: Federal Government
Study ID:
PHS - 6434
NCT ID:
NCT00476203
Start Date:
May 2007
Completion Date:
May 2011
Related Keywords:
- Breast Cancer
- Breast Cancer
- Yoga
- Quality of Life
- Obesity
- Fatigue
- Weight
- Breast Neoplasms
Name | Location |
|---|---|
| Fred Hutchinson Cancer Research Center | Seattle, Washington 98109 |
