Feasibility Clinical Study: Accuracy of the P2X7 Biomarker in Detection of Endometrial Cancers in Women
The present study aims at developing an accurate, simple and cost-effective method for
screening and early detection of uterine cancers in women using novel inventions and
biotechnology methods for collection and assay of uterine cells. Results of P2X7 assays
using tissues obtained from women with known uterine cancer and from women with
histologically normal endometrium will be compared. These data will also serve as basis for
future studies to test the predictive value of the method in population-based studies.
Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Screening
To determine the accuracy potential of the P2X7 (protein and mRNA levels) for the detection of uterine endometrial cancers in women.
Upon review of the assays.
Jay Pinkerton, MD
University Hospital Case Medical Center
United States: Institutional Review Board
|Eastern Virginia Medical School||Norfolk, Virginia 23507|
|University of Arkansas||Little Rock, Arkansas 72202|
|University of Texas||Houston, Texas 77225|
|University Hospital Case Medical Center||Cleveland, Ohio 44106|