A Contrast of Buffered Vs. Unbuffered Lidocaine in Bone Marrow Biopsies
- Any newly diagnosed patient at the Arthur G. James Cancer Hospital and Richard J.
Solove Research Institute whose Hematologist or Oncologist has ordered them to
undergo a bilateral bone marrow biopsy for diagnostic and /or treatment purposes.
- 18 years of age or older.
- Pregnant or Lactating women.
- Patients with allergies to local anesthetics.
- Patients requiring a unilateral bone marrow biopsy.
- Patients that cannot lie flat in either the supine or prone position.
- Patients that have used any of the following: narcotics, non-narcotic analgesia or an
anti-anxiolytic medication on the same calendar day as the scheduled procedure. These
medications will not be given to the participant at any time before or during the
- Patients on long-acting narcotic medication.
- Patients with neuropathy in the posterior iliac crest area
- Patients with a platelet count less than 20,000.
- Patients who are cognitively impaired or unable to self-report pain using the VAS.
- Patients with known bone metastasis.