TEACH Survey (Thrombo-Embolism And Chemotherapy) A Prospective Survey on the Incidence of Venous Thromboembolic Events During Chemotherapy for Solid Tumors
- Determine the incidence of venous thromboembolic events (i.e., deep vein thrombosis
and/or pulmonary embolism) in patients undergoing chemotherapy for solid tumors.
OUTLINE: This is a prospective, multicenter survey.
Patients undergo observation beginning on day 1 of chemotherapy and continuing for up to 3
months in the absence of symptomatic, confirmed deep vein thrombosis or pulmonary embolism;
use of anticoagulant therapy for more than 5 days as curative treatment; or initiation of
thromboprophylaxis for any reason. Patients undergo bilateral compression ultrasound of the
lower limbs at baseline and at 3 months (or at an earlier timepoint, if indicated).
PROJECTED ACCRUAL: A total of 2,000 patients will be accrued for this study.
Incidence of asymptomatic proximal deep vein thrombosis (DVT) of the lower limbs as assessed by bilateral compression ultrasound at baseline and at 3 months
Hans-Martin Otten, MD
United States: Federal Government