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Multi-Site Evaluation of a Video Game for Adolescents and Young Adults With Cancer

13 Years
29 Years
Not Enrolling

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Trial Information

Multi-Site Evaluation of a Video Game for Adolescents and Young Adults With Cancer

POPULATION: Approximately 340 patients will be enrolled in this study. Patients will be 13
to 29 years of age with any cancer (original diagnosis or relapse), currently receiving
treatment and expected to be on treatment for at least 4 - 6 months following Baseline
assessment, and able to communicate effectively in English, Spanish, or French.
Approximately 170 patients will be enrolled in each of the two treatment groups. Each group
will receive either the “Re-Mission” video game and a popular interactive video game, or
just the popular interactive video game.

DESIGN: This is a multi-center, randomized trial, with patients randomized to one of two
groups. One group (50% of patients) will receive the active intervention, which is the
psycho-educational video game module called Re-Mission and a popular video game (hereafter
“RE-MISSION”) and another group (50 % of patients) will be in a game control group and
receive a popular video game only (hereafter “GAME CONTROL. The games in the RE-MISSION and
GAME CONTROL groups are delivered on identical mini, personal computers (hereafter

INTERVENTION: Each patient in the RE-MISSION group will be asked to play “Re-Mission” along
with the popular video game for at least one hour a week for a period of ten to fourteen
weeks. “Re-Mission” presents a 3-D environment in which the player can manipulate a
humanoid character inside the virtual body of a patient with cancer. Game-play consists of
guiding the character to destroy cancer cells and other “enemies” in the body (e.g.,
bacteria) while avoiding injury or weakness. During the process of playing the game and
guiding the character through a series of missions, the player learns about chemotherapy and
other medical treatments, health-promoting self-care behaviors, infections, and pain
management. In addition, the game has also been designed to facilitate the patient’s
ability to share knowledge and concerns with others.

DURATION OF STUDY: 9 –12 months

Inclusion Criteria:

1. Male or female patient 13 to 29 years of age with a cancer diagnosis.

2. Patient who is currently receiving treatment and is expected to remain on treatment
for at least 4 – 6 months.

Exclusion Criteria:

1. Patient who has a history of seizures due to photosensitivity.

2. Patient who has been determined by the investigator to be incapable of following the
study schedule or study directions for any reason.

3. Patient who can not communicate effectively with study personnel in English, Spanish,
or French.

Type of Study:


Study Design:

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care

Outcome Measure:


Principal Investigator

Pamela M Kato

Investigator Role:

Principal Investigator

Investigator Affiliation:

HopeLab Foundation


United States: Institutional Review Board

Study ID:




Start Date:

October 2004

Completion Date:

November 2005

Related Keywords:

  • Neoplasms
  • Cancer
  • Video game
  • Adolescent
  • Young adult
  • Neoplasms



Deaconess Medical Center Spokane, Washington  99210-0248
Children's Hospital of Orange County Orange, California  92668
Children's Mercy Hospital Kansas City, Missouri  64108
All Children's Hospital St. Petersburg, Florida  33701
Driscoll Children's Hospital Corpus Christi, Texas  78466
Lucile Packard Children's Hospital at Stanford Palo Alto, California  94304
Children's Hospital of Austin Austin, Texas  78701
Children's Hospital of the King's Daughters Norfolk, Virginia  23507
City of Hope National Medical Center Los Angeles, California  91010
St. Joseph's Children's Hospital of Tampa Tampa, Florida  33677-4227
DeVos Children's Hospital Grand Rapids, Michigan  49503
Washington University St. Louis, Missouri  63110
Cook Children's Medical Center Fort Worth, Texas  76104
Los Angeles Children's Center for Cancer and Blood Disease Los Angeles, California  90027
Children's Hospital of SW Florida / Lee Memorial Health System Fort Myers, Florida  33908
Nemours Children's Clinic-Jacksonville Jacksonville, Florida  32207
Kapiolani Medical Center Honolulu, Hawaii  96826
LSU Children's Hospital of New Orleans New Orleans, Louisiana  70118
Dana-Farber Cancer Institute and Children's Hospital Boston, Massachusetts  02115
St John Van Elslander Cancer Center Grosse Pointe Woods, Michigan  48236
Children's Health Care - Minneapolis St. Paul, Minnesota  55404
Children's Hospital of New Mexico Albuquerque, New Mexico  87131-0001
Golisano Children's Hospital, University of Rochester Rochester, New York  14642
Warren Clinic / Saint Francis Hospital Tulsa, Oklahoma  74136
Doernbecher Childrens Hospital - OHSU Portland, Oregon  97239
Legacy Emanuel Children's Cancer Program Portland, Oregon  97227
Christus Santa Rosa Children’s Hospital San Antonio, Texas  78207