Proteomic Analysis of Serology and Peptides Presented on the HLA Complex of Breast, Ovarian, Colon, Rectal, Gastric and Pancreatic Adenocarcinoma.
N/A
N/A
Both
Colorectal Neoplasms, Stomach Neoplasms, Pancreatic Neoplasms, Breast Neoplasms, Ovarian Cancer
Trial Information
Proteomic Analysis of Serology and Peptides Presented on the HLA Complex of Breast, Ovarian, Colon, Rectal, Gastric and Pancreatic Adenocarcinoma.
The main objective of the study is to evaluate which proteins are presented by the HLA
complex of solid tumors. Secondary objectives include to evaluate whether an immune
response specific to these proteins has actually been provoked and whether there is a
similar immune response following recurrence. Real specimens will be evaluated using PCR and
mass spectrometry.
Inclusion Criteria:
- Patients with adenocarcinoma of breast, colon, rectum, ovary , stomach, pancreas
Exclusion Criteria:
- Withdrawal of consent
- Small specimen which does not allow to retrieve tissue without interfering with
pathologic evaluation
Type of Study:
Observational
Study Design:
Additional Descriptors: Convenience Sample, Observational Model: Natural History, Time Perspective: Longitudinal, Time Perspective: Prospective
Principal Investigator
Itamar Ashkenazi, M.D.
Investigator Role:
Principal Investigator
Investigator Affiliation:
Hillel Yaffe Medical Center
Authority:
Israel: Ethics Commission
Study ID:
ProtHYMC
NCT ID:
NCT00419627
Start Date:
February 2007
Completion Date:
Related Keywords:
- Colorectal Neoplasms
- Stomach Neoplasms
- Pancreatic Neoplasms
- Breast Neoplasms
- Ovarian Cancer
- proteomics of solid tumors
- Breast Neoplasms
- Neoplasms
- Colorectal Neoplasms
- Stomach Neoplasms
- Ovarian Neoplasms
- Pancreatic Neoplasms
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