Development of a Geriatric Assessment Measure for Older Patients With Cancer
- Determine the feasibility of administration of the geriatric assessment in elderly
patients with cancer.
- Determine the percentage of patients able to complete the self-administered portion of
the geriatric assessment without assistance.
- Determine the length of time necessary to complete the geriatric assessment.
- Determine the variance and number of missing items.
- Assess patient satisfaction with the questionnaire by identifying items that are
distressing or difficult to comprehend.
- Assess the percentage of geriatric assessments that contain all three of the following
items: Timed Up and Go Assessment, Blessed Orientation-Memory-Concentration Test, and
healthcare professional-rated Karnofsky performance status.
- Determine the proportion of patients who are able to complete the self-report portion
of the questionnaire without assistance and the length of time needed to complete the
geriatric assessment within patients of various sociodemographic factors and
OUTLINE: This is a multicenter study. Patients are stratified according to age (65 to 69
years vs 70 years and over).
Patients undergo assessments of cognition using the Blessed Orientation-Memory-Concentration
Test; functional status using the Timed Up and Go Assessment (measures physical mobility);
and performance status using the healthcare professional-rated Karnofsky performance scale.
These assessments are performed by healthcare personnel. Body mass index and the percentage
of unintentional weight loss and the number of falls in the past 6 months are also assessed.
Patients also complete the following self-administered questionnaires: Instrumental
Activities of Daily Living (measures level of functioning and need for services); Activities
of Daily Living (measures higher levels of physical functioning); Karnofsky Self-Reported
Performance Rating Scale (related to survival and clinically significant illness); Physical
Health Section of the Older American Resources and Services Questionnaire (measures
comorbidity and the impact on daily activities); Hospital Anxiety and Depression Scale;
Medical Outcomes Study (MOS) Social Activity Limitations Measure (measures the impact of
cancer on patients' social functioning); and MOS Social Support Survey Emotional/Information
and Tangible Subscales (measures perceived availability of social support).
Patients then begin planned treatment.
PROJECTED ACCRUAL: A total of 80 patients will be accrued for this study.
Mean and median time to complete the entire geriatric assessment
Alice B. Kornblith, PhD
Dana-Farber Cancer Institute
United States: Federal Government
|Duke Comprehensive Cancer Center||Durham, North Carolina 27710|
|Memorial Hospital of South Bend||South Bend, Indiana 46601|
|CCOP - Northern Indiana CR Consortium||South Bend, Indiana 46601|
|Saint Joseph Regional Medical Center||South Bend, Indiana 46617|
|CCOP - Hematology-Oncology Associates of Central New York||East Syracuse, New York 13057|
|CCOP - Nevada Cancer Research Foundation||Las Vegas, Nevada 89109-2306|
|Elkhart General Hospital||Elkhart, Indiana 46515|
|Howard Community Hospital||Kokomo, Indiana 46904|
|Lakeland Regional Cancer Care Center - St. Joseph||St. Joseph, Michigan 49085|
|University Medical Center of Southern Nevada||Las Vegas, Nevada 89102|
|Center for Cancer Therapy at LaPorte Hospital and Health Services||La Porte, Indiana 46350|
|Michiana Hematology-Oncology, PC - South Bend||Mishawaka, Indiana 46545-1470|
|Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center||Columbus, Ohio 43210-1240|