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Development of a Geriatric Assessment Measure for Older Patients With Cancer

65 Years
Not Enrolling
Unspecified Adult Solid Tumor, Protocol Specific

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Trial Information

Development of a Geriatric Assessment Measure for Older Patients With Cancer



- Determine the feasibility of administration of the geriatric assessment in elderly
patients with cancer.

- Determine the percentage of patients able to complete the self-administered portion of
the geriatric assessment without assistance.

- Determine the length of time necessary to complete the geriatric assessment.

- Determine the variance and number of missing items.

- Assess patient satisfaction with the questionnaire by identifying items that are
distressing or difficult to comprehend.

- Assess the percentage of geriatric assessments that contain all three of the following
items: Timed Up and Go Assessment, Blessed Orientation-Memory-Concentration Test, and
healthcare professional-rated Karnofsky performance status.


- Determine the proportion of patients who are able to complete the self-report portion
of the questionnaire without assistance and the length of time needed to complete the
geriatric assessment within patients of various sociodemographic factors and
educational status.

OUTLINE: This is a multicenter study. Patients are stratified according to age (65 to 69
years vs 70 years and over).

Patients undergo assessments of cognition using the Blessed Orientation-Memory-Concentration
Test; functional status using the Timed Up and Go Assessment (measures physical mobility);
and performance status using the healthcare professional-rated Karnofsky performance scale.
These assessments are performed by healthcare personnel. Body mass index and the percentage
of unintentional weight loss and the number of falls in the past 6 months are also assessed.

Patients also complete the following self-administered questionnaires: Instrumental
Activities of Daily Living (measures level of functioning and need for services); Activities
of Daily Living (measures higher levels of physical functioning); Karnofsky Self-Reported
Performance Rating Scale (related to survival and clinically significant illness); Physical
Health Section of the Older American Resources and Services Questionnaire (measures
comorbidity and the impact on daily activities); Hospital Anxiety and Depression Scale;
Medical Outcomes Study (MOS) Social Activity Limitations Measure (measures the impact of
cancer on patients' social functioning); and MOS Social Support Survey Emotional/Information
and Tangible Subscales (measures perceived availability of social support).

Patients then begin planned treatment.

PROJECTED ACCRUAL: A total of 80 patients will be accrued for this study.

Inclusion Criteria


- Histologically confirmed malignancy at any stage

- Enrolled on any cooperative group-sponsored cancer treatment trial (treatment has not
yet started), including trials on the Cancer Trials Support Unit


- Any performance status allowed

- Must be able to follow directions in English

- Sufficient cognitive and psychological function to give consent


- See Disease Characteristics

Type of Study:


Study Design:


Outcome Measure:

Mean and median time to complete the entire geriatric assessment

Principal Investigator

Alice B. Kornblith, PhD

Investigator Role:

Study Chair

Investigator Affiliation:

Dana-Farber Cancer Institute


United States: Federal Government

Study ID:




Start Date:

December 2006

Completion Date:

Related Keywords:

  • Unspecified Adult Solid Tumor, Protocol Specific
  • unspecified adult solid tumor, protocol specific



Duke Comprehensive Cancer Center Durham, North Carolina  27710
Memorial Hospital of South Bend South Bend, Indiana  46601
CCOP - Northern Indiana CR Consortium South Bend, Indiana  46601
Saint Joseph Regional Medical Center South Bend, Indiana  46617
CCOP - Hematology-Oncology Associates of Central New York East Syracuse, New York  13057
CCOP - Nevada Cancer Research Foundation Las Vegas, Nevada  89109-2306
Elkhart General Hospital Elkhart, Indiana  46515
Howard Community Hospital Kokomo, Indiana  46904
Lakeland Regional Cancer Care Center - St. Joseph St. Joseph, Michigan  49085
University Medical Center of Southern Nevada Las Vegas, Nevada  89102
Center for Cancer Therapy at LaPorte Hospital and Health Services La Porte, Indiana  46350
Michiana Hematology-Oncology, PC - South Bend Mishawaka, Indiana  46545-1470
Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center Columbus, Ohio  43210-1240