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Pattern of Cell Death Following Neoadjuvant Therapy for Metastatic Colon Cancer


N/A
18 Years
N/A
Not Enrolling
Both
Metastatic Colorectal Cancer

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Trial Information

Pattern of Cell Death Following Neoadjuvant Therapy for Metastatic Colon Cancer


Inclusion Criteria:



- Patients must be ≥ 18 years old.

- Patients must have colon cancer metastases to the liver.

- Patients must be candidates and be scheduled for liver resection.

- Patients must have received and have had a response to neoadjuvant therapy prior to
liver resection.

- Patients must have signed Institutional Review Board (IRB) approved written consent
form prior to registering in the study.

Exclusion Criteria:

- Patients who are < 18 years old.

- Patients who do not have colon cancer metastases to the liver.

- Patients who are not surgical candidates.

- Patients who do not schedule or who cancel a liver resection.

- Patients who have not received neoadjuvant therapy.

- Patients who have received neoadjuvant therapy but who have had no response or who
have had tumor progression.

Type of Study:

Observational

Study Design:

Observational Model: Case-Only, Time Perspective: Prospective

Principal Investigator

Michael A Choti, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Johns Hopkins University

Authority:

United States: Institutional Review Board

Study ID:

J06106

NCT ID:

NCT00414492

Start Date:

December 2006

Completion Date:

June 2010

Related Keywords:

  • Metastatic Colorectal Cancer
  • metastatic colorectal cancer
  • liver metastasis
  • tumor margins
  • neoadjuvant therapy
  • Colonic Neoplasms
  • Colorectal Neoplasms

Name

Location

Johns Hopkins Medicine Baltimore, Maryland  21287