Chemoradiation-Induced Nausea and Emesis: A Prospective Study to Assess Patient Preferences and Quality of Life
You will be interviewed about your perceptions of side effects that are related to your
chemoradiation treatment. The interview will take about 20 minutes. You will be
interviewed at the beginning of your chemoradiation treatment, 3 weeks after treatment
starts, and at the first follow-up appointment after chemoradiation treatment ends.
Chemoradiation is a type of cancer treatment that involves both chemotherapy and radiation
You will also receive a packet of 3 questionnaires to complete at different times during and
after treatment. The questionnaires include a quality of life survey that asks about
physical, social, and emotional well-being, a self-report symptom evaluation that will ask
whether you are experiencing any particular side effects and if so how much it bothers you,
and a brief survey to asks questions about anxiety and distress.
The questionnaires should take about 20 minutes each to complete. The questionnaire packet
will be given to patients at the beginning of chemoradiation treatment, 3 weeks after
treatment starts, the last day of treatment, and at the first follow-up appointment after
chemoradiation treatment ends. If the you do not have time to complete the questionnaires,
a stamped, addressed envelop will be given so that you can mail the completed packet back to
the research team.
Your participation in this research study will be over about 4-6 weeks after chemoradiation
This is an investigational study. Up to 208 individuals (104 patients and 104 caregivers)
will take part in this study. All will be enrolled at M. D. Anderson.
Observational Model: Case Control, Time Perspective: Prospective
Longitudinal Quality of Life + Symptom Assessment Data
Quality of life survey instruments scored according to EORTC QLQ-C30 scoring manual. Patients and controls compared with respect to preference data. The control group preference data collected at only 1 time point, but patient preference data from each time point will be compared to these control group preference data.
Survey(s) & Interveiw(s) at baseline (beginning of chemoradiation treatment), 3 weeks after treatment starts, the last day of treatment, and at the first follow-up appointment after chemoradiation treatment ends.
Charlotte C. Sun, MD
M.D. Anderson Cancer Center
United States: Institutional Review Board
|UT MD Anderson Cancer Center||Houston, Texas 77030|