Feasibility of Radio-Frequency Ablation in the Management of Papillary Thyroid Cancer Under Ultra-Sound Guidance
Around 23,000 cases of thyroid cancer are discovered annually in the US, and PTC accounts
for 70-75% of those cases. The conventional treatment consists mainly of surgical resection,
in the form of lobectomy with/without isthmusectomy, or total thyroidectomy, making it one
of the most commonly performed procedures. It has high costs, and exposes the patients to
morbidity of surgery and anesthesia. PTC tends to be indolent with a 90% cure rate and
controversy exists regarding extent of treatment.
Percutaneous image-guided RFA has received increasing attention as a promising minimally
invasive technique for the treatment of focal malignant disease. It permits the in situ
destruction of tumors without necessitating their surgical excision.
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
After the procedure, each patient will have his/her routine post-operative care and the follow up visits for surgery, without additional specified visits or procedures for the study
Kieran Murphy, M.D
Johns Hopkins University
United States: Institutional Review Board
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