Trial Information

A Pilot Study to Evaluate Ultrasonic Surgical Aspiration as a Treatment Modality for Cervical Dysplasia

Women age 18 to 55 years of age with Cervical Intraepithelial Neoplasia 2 or 3 on colposcopy
with a negative EndoCervical Curettage are enrolled in a pilot study comparing ultrasonic
surgical aspiration and traditional cervical excision procedure for the treatment of
cervical dysplasia. In this pilot study, the patients serve as their own control group.
Prior to receiving the traditional treatment for cervical dysplasia consisting of Cold Knife
Conization with EndoCervical Curettage, each patient's cervix is treated with ultrasonic
surgical aspiration. The aspirate is sent to pathology and the results compared with the
findings from the cervical cone biopsy. The patients then are followed with Liquid-based
Cytology pap smears every 4 to 6 months until completion of the study enrollment/treatment
period.