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Collection of Blood for Gene Expression/Genomic Studies in Individuals With Chronic Lung Disease

18 Years
Open (Enrolling)
Asthma, COPD, Interstitial Lung Disease, Cystic Fibrosis, Lung Cancer

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Trial Information

Collection of Blood for Gene Expression/Genomic Studies in Individuals With Chronic Lung Disease

The investigators hope to be able to identify an association between a genetic make-up in
the blood samples and the risks of developing a particular lung disease, or severity of a
lung disease. The findings of this study might be important to develop future preventative
methods and potential treatments for the management of lung disease. The investigators aim
to collect blood samples from 300 people with lung disease and 300 controls over 5 years.

Inclusion Criteria:

- Must provide informed consent

- Males and females, age 18 years and older

- Lung disease proven by at least one of the following:

- symptoms consistent with pulmonary disease

- chest X-rays consistent with lung disease

- pulmonary function tests consistent with lung disease

- lung biopsy consistent with lung disease

- family history of lung disease

- disease of organs with know associated with lung disease

- individuals suspected of history of lung disease based on history and/or
physical examination

- normal controls (individuals without history of lung disease) to be sampled to
provide a comparison to the lung disease cohort.

Exclusion Criteria:

- Drug and/or alcohol abuse within the past six months

- Females who are pregnant or nursing

Type of Study:


Study Design:

Observational Model: Case Control, Time Perspective: Prospective

Principal Investigator

Ronald G Crystal, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

The New York Presbyterian Hospital -- Weill Medical College of Cornell University


United States: Institutional Review Board

Study ID:




Start Date:

September 2005

Completion Date:

September 2013

Related Keywords:

  • Asthma
  • COPD
  • Interstitial Lung Disease
  • Cystic Fibrosis
  • Lung Cancer
  • Asthma
  • Cystic Fibrosis
  • Fibrosis
  • Lung Diseases
  • Lung Neoplasms
  • Pulmonary Fibrosis
  • Lung Diseases, Interstitial



New York Presbyterian Hospital -- Weill Cornell Medical College of Cornell UniversityNew York, New York  10021