Colorectal Cancer Screening Intervention for Family Members of Colorectal Cancer Patients
- Compare the impact of 3 interventions (generic educational print intervention, tailored
educational print intervention, or tailored educational print intervention plus
telephone counseling) on colorectal cancer screening behaviors and intentions among
siblings at increased familial risk for colorectal cancer.
- Determine whether demographic factors, medical access, physician recommendation at
baseline, and proband (patient) characteristics (e.g., stage of disease) moderate the
impact of the interventions on colorectal screening.
- Evaluate whether knowledge, attitude, and physician recommendation variables mediate
the association between the interventions and colorectal screening, and determine
whether these variables are impacted by the interventions.
- Analyze the cost of each intervention.
OUTLINE: This is a randomized, controlled, cohort, multicenter study. Participants are
stratified according to study site. Participants are randomized to 1 of 3 intervention arms.
- Arm I: Participants receive generic educational print intervention approximately 1 week
after completing the baseline survey.
- Arm II: Participants receive tailored educational print intervention within 10 days
after completing the baseline survey and a tailored newsletter 1 month after completing
the baseline survey.
- Arm III: Participants receive tailored educational print intervention approximately
14-18 days after completing the baseline survey. Participants undergo a telephone
counseling session within 2 weeks after receiving the tailored print intervention and
receive a tailored newsletter 1 month after completing the baseline survey.
After study completion, participants are followed at 6 months and/or 1 year.
PROJECTED ACCRUAL: A total of 660 participants will be accrued for this study.
Colorectal cancer screening compliance
Sharon Manne, PhD
Fox Chase Cancer Center
United States: Federal Government
|Memorial Sloan-Kettering Cancer Center||New York, New York 10021|
|Massachusetts General Hospital Cancer Center||Boston, Massachusetts 02114|
|M.D. Anderson Cancer Center at University of Texas||Houston, Texas 77030|
|Hunterdon Regional Cancer Center at Hunterdon Medical Center||Flemington, New Jersey 08822|
|Lombardi Comprehensive Cancer Center at Georgetown University Medical Center||Washington, District of Columbia 20007|
|Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School||New Brunswick, New Jersey 08903|
|Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital Marlton||Marlton, New Jersey 08053|
|Fox Chase Cancer Center - Philadelphia||Philadelphia, Pennsylvania 19111-2497|
|St. Mary Regional Cancer Center||Langhorne, Pennsylvania 19047|
|Pottstown Memorial Regional Cancer Center||Pottstown, Pennsylvania 19464|
|McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center||Reading, Pennsylvania 19612-6052|
|Fox Chase Cancer Center CCOP Research Base||Philadelphia, Pennsylvania 19140|
|PinnacleHealth Regional Cancer Center at Polyclinic Hospital||Harrisburg, Pennsylvania 17105|
|Franklin & Edith Scarpa Regional Cancer Center at South Jersey Healthcare||Vineland, New Jersey 08360|
|H. Lee Moffitt Cancer Center CCOP Research Base||Tampa, Florida 33612|
|Helen F. Graham Cancer Center at Christiana Care||Newark, Delaware 19713|
|Presbyterian Medical Center||Philadelphia, Pennsylvania 19104|
|Northeast Regional Cancer Institute||Scranton, Pennsylvania 18510|