In Vitro Study of Peripheral Blood Mononuclear Cell Function in Healthy Individuals and Patients
Peripheral blood mononuclear cells (PBMC) will be collected from healthy volunteers and
patients who present with different diseases that involve or implicate the immune system
dysregulation (HIV infection, autoimmune diseases and cancer). These PBMC will be studied
in vitro for a number of functional parameters, including generating soluable factors that
inhibit HIV infection, developing patterns of immune dysregulation, and inducing apoptotic T
cell death. The purpose of such studies is to obtain insight into the mechanisms of natural
resistance to viral infections, AIDS pathogenesis, and disease-induced immune dysregulation.
Observational
N/A
United States: Federal Government
999993010
NCT00342485
April 1993
March 2008
Name | Location |
---|---|
Willford Hall USAF Medical Center | San Antonio, Texas 78236 |