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Isolation and Characterization of Mammary Stem Cells


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N/A
Not Enrolling
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Stem Cells

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Trial Information

Isolation and Characterization of Mammary Stem Cells


Cancers are composed of heterogeneous populations of cells with varying degrees of
proliferative capacity and ability to reconstitute tumors when transplanted into nude or
SCID mice.

Recently, cancer stem cells have been identified as a small population of tumor cells which
possess the stem cell properties in that their self-renewal pathway is highly deregulated.
This deregulation seems to be the prerequisite for the development of cancer.

Inclusion Criteria


- INCLUSION CRITERIA:

The tissue samples will come from the human cooperative network. They have their own set
of criteria. We are requesting tissue samples from individuals that are normal as well as
those who have cancer.

EXCLUSION CRITERIA:

The tissue samples will come from the human cooperative tissue network and we are asking
for normal samples from individuals who don't have any opportunistic diseases.

Type of Study:

Observational

Study Design:

N/A

Authority:

United States: Federal Government

Study ID:

999906140

NCT ID:

NCT00340392

Start Date:

April 2006

Completion Date:

March 2011

Related Keywords:

  • Stem Cells
  • Mammary Stem Cells
  • Breast Cancer
  • Cancer Stem Cells
  • Gene Expression Profiling

Name

Location

National Cancer Institute (NCI), 9000 Rockville Pike Bethesda, Maryland  20892