Isolation and Characterization of Mammary Stem Cells
Cancers are composed of heterogeneous populations of cells with varying degrees of
proliferative capacity and ability to reconstitute tumors when transplanted into nude or
SCID mice.
Recently, cancer stem cells have been identified as a small population of tumor cells which
possess the stem cell properties in that their self-renewal pathway is highly deregulated.
This deregulation seems to be the prerequisite for the development of cancer.
Observational
N/A
United States: Federal Government
999906140
NCT00340392
April 2006
March 2011
Name | Location |
---|---|
National Cancer Institute (NCI), 9000 Rockville Pike | Bethesda, Maryland 20892 |