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US-Doppler and Procoagulant Microparticles for the Diagnosis of Asymptomatic DVT in Advanced Cancer Patients With Poor Performance Status


N/A
18 Years
N/A
Not Enrolling
Both
Deep Vein Thrombosis, Cancer

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Trial Information

US-Doppler and Procoagulant Microparticles for the Diagnosis of Asymptomatic DVT in Advanced Cancer Patients With Poor Performance Status


The association between malignancy and venous thromboembolism(VTE) is well known. VTE is one
of the most common complications seen in cancer patients Early detection of VTE can identify
patients who may benefit from anticoagulant therapy and prevent morbidity and mortality.

There are recommendations for hospitalized cancer patients who are bedridden with an acute
medical illness to receive prophylaxis, but in practice this is not clear cut.It has been
shown, in other selected groups of patients that Ultrasound Doppler can be used in order to
diagnose asymptomatic DVT (deep vein thrombosis). Hematological coagulation tests,
including procoagulant microparticles will be performed for the evaluation of coagulation
profile, in order to evaluate the possible correlation between the prevalence of
asymptomatic DVT and these laboratory parameters.


Inclusion Criteria:



- Cancer patients with an advanced stage of the disease, hospitalized in the oncology
department.

- WHO performance status of 3( i.e. spends more than half his/her time in bed or
seated) - or 4 ( i.e. completely confined to bed or to chair) : for at least a week;
according to the treating physician, the poor performance status results from
advanced malignancy.

- Patient is asymptomatic for lower extremity DVT according to the treating physician

Exclusion Criteria:

- major surgery during more than a month, from the time of investigation

- anticoagulant therapy for more than one month, from the time of investigation

Type of Study:

Observational

Study Design:

Observational Model: Case-Only, Time Perspective: Prospective

Principal Investigator

Nira Beck-Razi

Investigator Role:

Principal Investigator

Investigator Affiliation:

Ministry of Health, Israel

Authority:

Israel: Israeli Health Ministry Pharmaceutical Administration

Study ID:

BECKCTIL

NCT ID:

NCT00336258

Start Date:

June 2006

Completion Date:

December 2010

Related Keywords:

  • Deep Vein Thrombosis
  • Cancer
  • Deep Vein Thrombosis
  • Cancer
  • US- Doppler
  • Procoagulant Microparticles
  • Asymptomatic
  • Thrombosis
  • Venous Thrombosis

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