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Program for the Assessment of Clinical Cancer Tests (PACCT-1): Trial Assigning Individualized Options for Treatment: The TAILORx Trial

Phase 3
18 Years
75 Years
Open (Enrolling)
Estrogen Receptor-positive Breast Cancer, HER2-negative Breast Cancer, Progesterone Receptor-positive Breast Cancer, Stage IA Breast Cancer, Stage IB Breast Cancer, Stage II Breast Cancer, Stage IIIB Breast Cancer

Thank you

Trial Information

Program for the Assessment of Clinical Cancer Tests (PACCT-1): Trial Assigning Individualized Options for Treatment: The TAILORx Trial


I. To determine whether adjuvant hormonal therapy is not inferior to adjuvant chemohormonal
in women whose tumors meet established clinical guidelines for adjuvant chemotherapy and
fall in the "primary study group" category (Oncotype DX Recurrence Score 11-25).

II. To create a tissue and specimen bank for patients enrolled in this trial, including
formalin fixed paraffin embedded tumor specimens, tissue microarrays, plasma, and DNA
obtained from peripheral blood.


I. To determine whether adjuvant hormonal therapy is sufficient treatment (i.e. 10 year
distant disease-free survival of at least 95%) for women whose tumors meet established
clinical guidelines for adjuvant chemotherapy and who fall into the "Secondary Study
Group-1" category (Oncotype DX Recurrence Score =< 10).

II. To compare the outcomes projected at 10 years by Adjuvant! (with outcomes projected
using classical pathologic information including tumor size, hormone receptor status, and
histologic grade) with those made by the Genomic Health Oncotype DX test. Classical
pathologic information and outcome results will also be used to create and refine models
that would use classical information instead of or in combination with genomic tests.

III. To estimate failure rates as a function of RS separately in the chemotherapy (arms C,
D) and no chemotherapy (arms A, B) groups. The purpose of the analysis is to develop more
precise estimates of the relationship between recurrence score and chemotherapy treatment
effect, if any, at the upper range of the RS 11 - 25 group.

IV. RS gene groups (proliferation gene group, HER2 gene group, ER gene group, invasion gene
group, and other genes).


I. To evaluate the effects of chemotherapy and hormonal therapy vs hormonal therapy alone on
perceived cognitive impairment, fatigue, fear of recurrence among pre-menopausal patients,
endocrine symptoms and sexual dysfunction, and overall health-related quality of life

II. To determine whether perceived cognitive impairment, fatigue, fear of recurrence,
endocrine symptoms, and overall HRQL are similar for patients receiving chemotherapy plus
hormonal therapy in secondary study group 2 as for those in the primary study group (arm D
vs C).

III. To determine whether perceived cognitive impairment, fatigue, fear of recurrence,
endocrine symptoms, and overall HRQL are similar for patients receiving hormonal therapy
alone in secondary study group 1 as for those in the primary study group (arms A vs B).

IV. To determine whether age will be inversely associated with a fear of recurrence,
independent of treatment assignment.

V. Among participants receiving hormonal treatment alone on arm A and arm B, to determine
whether ODRS will be inversely correlated with fear of recurrence.

VI. To create a biospecimen repository including plasma, serum and CellSearch cassettes
containing circulating tumor cells (CTC) for evaluating determinants of late relapse,
including candidate biomarkers reflecting occult tumor burden (e.g., CTCs and plasma tumor
DNA) and host factors (e.g., estrogen, insulin-IGF axis, inflammation, etc).

VII. To create a biorepository of metastatic tumor samples in patients who have had a late

VIII. To determine body mass index (BMI) and comorbidity burden in patients with operable
breast cancer five or more years after diagnosis.

IX. To determine whether there is a relationship between late relapse and BMI at diagnosis
and at 5 years after diagnosis, and whether BMI-associated inflammatory and/or metabolic
biomarkers are associated with early and late recurrence.

OUTLINE: This is a multicenter, partially randomized study. Patients are assigned to 1 of 3
treatment groups based on their risk of distant recurrence determined by Oncotype DX Breast
Cancer Assay.

receive standard hormonal therapy (e.g., oral tamoxifen alone, oral aromatase inhibitor
[e.g., anastrozole, letrozole, or exemestane] alone, or oral tamoxifen followed by oral
aromatase inhibitor) at the discretion of the treating physician for 5 or 10 years.

GROUP 2 (PRIMARY STUDY GROUP; ODRS 11-25): Patients are stratified according to tumor size
(≤ 2.0 cm vs ≥ 2.1 cm), menopausal status (postmenopausal vs premenopausal vs
perimenopausal), planned chemotherapy (taxane-containing [i.e., paclitaxel, docetaxel] vs
nontaxane-containing), planned radiotherapy (whole breast with no boost planned vs whole
breast with boost planned vs partial breast irradiation planned vs no planned radiation
therapy [for patients who have had a mastectomy]) and Oncotype DX Recurrence Score (11-15 vs
16-20 vs 21-25). Patients are then randomized to receive either hormonal therapy alone or
combination chemotherapy and hormonal therapy.

ARM I (EXPERIMENTAL): Patients receive hormonal therapy as in group 1 at the discretion of
the treating physician.

ARM II (STANDARD): Patients receive standard combination chemotherapy at the discretion of
the treating physician. Within 4 weeks after the last dose of chemotherapy, patients receive
hormonal therapy as in group 1 at the discretion of the treating physician.

GROUP 3 (SECONDARY STUDY GROUP 2; ODRS > 25): Patients receive combination chemotherapy as
in group 2, arm II followed by hormonal therapy as in group 1.

Patients in all groups who have had breast-conservation surgery are also treated with
radiotherapy. Radiotherapy should begin within 4 weeks of registration for patients
receiving hormonal therapy alone or within 8 weeks after completion of chemotherapy.
Patients participating in NSABP and/or RTOG partial irradiation trial(s) may receive partial
breast radiation.

Tissue obtained at surgery (performed prior to study entry) is examined by the Oncotype DX
Recurrence Score Assay and other assays to correlate response with various biomarkers.
Patients may complete quality-of-life assessments at baseline and at 3, 6, 12, 24, and 36

After completion of study treatment, patients are followed up periodically for up to 20

Inclusion Criteria:

- Patients with operable histologically confirmed adenocarcinoma of the female breast
who have completed primary surgical treatment and meet the following criteria

- ER and/or progesterone receptor (PR)-positive: Estrogen and/or progesterone
receptor positive disease (as defined by local pathology laboratory).

- Negative axillary nodes: As assessed by a sentinel lymph node biopsy, an
axillary dissection, or both, and as defined by the Sixth Edition of the
American Joint Committee on Cancer (AJCC) staging criteria

- Tumor size 1.1-5.0 cm (or 5 mm-1.0 cm plus unfavorable histological features):

- Unfavorable features defined as intermediate or poor nuclear and/or
histologic grade, or lymphovascular invasion

- NOTE: Definition of tumor size: The tumor size used for determination of
eligibility is the pathologic tumor size, which is usually determined by
the size of the tumor as measured by inspection of the gross specimen; if
the tumor size is measured microscopically and the tumor includes ductal
carcinoma in-situ, the measurement should include only the invasive
component of the tumor

- The tumor must be Her2/neu negative by either fluorescent in-situ hybridization
(FISH) or immunohistochemistry (e.g. 0 or 1+ by DAKO Herceptest)

- The patient and physician must be agreeable to initiate standard chemotherapy and
hormonal therapy as adjuvant therapy

- A tissue specimen from the primary breast cancer has been located and is ready to be
shipped to the appropriate laboratory after consent is obtained and within 3 days
following pre-registration NOTE: For determination of the Oncotype Recurrence Score,
tissue must be shipped to Genomic Health; if the Oncotype DX Recurrence Score was
previously performed by Genomic Health (prior to pre-registration), tissue must be
submitted to the ECOG Pathology Coordinating Office upon randomization

- Leukocyte count ≥ 3500/ mm^3

- Platelets ≥ 100,000/mm^3

- Serum creatinine ≤ 1.5 mg/dL

- Serum aspartate transaminase (AST) that is ≤ 3-fold the upper institutional limits of

- Patients must be disease-free of prior invasive malignancies for ≥ 5 years with the
exception of curatively-treated basal cell or squamous cell carcinoma of the skin or
carcinoma in situ of the cervix; patients with a previous ipsilateral or
contralateral invasive breast cancer, or with bilateral synchronous cancers, are not
eligible; patients with previous ipsilateral or contralateral ductal in situ
carcinoma (DCIS) are not eligible

- Prior treatment

- Mandatory prior surgery criteria:

- Patient must pre-register within 84 days from the final surgical procedure
required to adequately treat the primary tumor (Please note that if margins
are not clear and a resection has to be conducted after pre-registration
but before randomization, the patient will be deemed to be within the 84
day window allowed by protocol and therefore eligible)

- All tumors should be removed by either a mastectomy or local excision plus
an acceptable axillary procedure (i.e., sentinel lymph node biopsy,
axillary dissection, or both); there must be adequate (at least 1 mm if
margin width specified) tumor-free margins of resection (for invasive and
ductal carcinoma in-situ) in order for the patients to be eligible;
patients with lobular carcinoma in-situ involving the resection margins are

- Criteria re: other prior treatments:

- No prior chemotherapy for this malignancy

- No prior radiation therapy for this malignancy; this includes no prior
MammoSite Brachytherapy radiation therapy (RT)

- Hormonal therapy: Patients who develop breast cancer while receiving a
selective estrogen-receptor modulator (SERM; e.g., tamoxifen,
toremifene, raloxifene) or an aromatase inhibitor (e.g., anastrazole,
letrozole, exemestane) for breast cancer prevention or a SERM for
other indications (e.g., raloxifene for osteoporosis) are not
eligible; however, patients may have received up to 8 weeks of a SERM
or aromatase inhibitor for this malignancy and still be eligible for
study entry

- Patients must have an anticipated life expectancy of at least 10 years

- Patients with the following medical conditions should not be enrolled on the study:

- Chronic obstructive pulmonary disease requiring treatment

- Chronic liver disease (e.g., cirrhosis, chronic active hepatitis)

- Previous history of a cerebrovascular accident

- History of congestive heart failure or other cardiac disease that would
represent a contraindication to the use of an anthracycline (e.g., doxorubicin
or epirubicin)

- Chronic psychiatric condition or other condition that would impair compliance
with the treatment regimen

- Women must not be pregnant or breast-feeding; all females of childbearing potential
must have a blood test or urine study within 2 weeks prior to pre-registration to
rule out pregnancy

- Women of childbearing potential must be strongly advised to utilize an accepted
and effective form of non-hormonal contraception (e.g. intrauterine device,
condoms, diaphragm, abstinence)

- Patients must not have previously had the Oncotype DX Assay performed, with the
exception of patients who have had the assay performed and have a recurrence score of

Type of Study:


Study Design:

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Outcome Measure:

Disease-free survival

Outcome Description:

DFS will be compared using a stratified log rank test.

Outcome Time Frame:

Date of randomization or registration to the date of ipsilateral breast tumor recurrence, local/regional recurrence, distant recurrence, second primary cancer (breast or non-breast), or death from any cause, assessed up to 10 years

Safety Issue:


Principal Investigator

Joseph Sparano

Investigator Role:

Principal Investigator

Investigator Affiliation:

Eastern Cooperative Oncology Group


United States: Food and Drug Administration

Study ID:




Start Date:

April 2006

Completion Date:

Related Keywords:

  • Estrogen Receptor-positive Breast Cancer
  • HER2-negative Breast Cancer
  • Progesterone Receptor-positive Breast Cancer
  • Stage IA Breast Cancer
  • Stage IB Breast Cancer
  • Stage II Breast Cancer
  • Stage IIIB Breast Cancer
  • Breast Neoplasms



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Methodist HospitalHouston, Texas  77030
Aurora Sinai Medical CenterMilwaukee, Wisconsin  53201-0342
Sharp Memorial HospitalSan Diego, California  92123
Martin Memorial Cancer CenterStuart, Florida  34995-9010
Greene Memorial HospitalXenia, Ohio  45385
Easton HospitalEaston, Pennsylvania  18042
Saint Joseph's Mercy Cancer CenterHot Springs, Arkansas  71913
Hospital of Saint RaphaelNew Haven, Connecticut  06511
Greater Baltimore Medical CenterBaltimore, Maryland  21204
Lowell General HospitalLowell, Massachusetts  01854
Rutherford HospitalRutherfordton, North Carolina  28139
Three Rivers Community HospitalGrants Pass, Oregon  97527
Providence Medford Medical CenterMedford, Oregon  97504
Harold Alfond Center for Cancer CareAugusta, Maine  04330
Union Hospital of Cecil CountyElkton MD, Maryland  21921
Miriam HospitalProvidence, Rhode Island  02906
Northridge Hospital Medical CenterNorthridge, California  91328
Presbyterian HospitalCharlotte, North Carolina  28233-3549
Mayo Clinic in FloridaJacksonville, Florida  32224
Sutter Roseville Medical CenterRoseville, California  95661
Manchester Memorial HospitalManchester, Connecticut  06040-4188
Washington Hospital CenterWashington, District of Columbia  20010
Saint James Hospital and Health Centers Comprehensive Cancer InstituteOlympia Fields, Illinois  60461
Memorial Medical CenterSpringfield, Illinois  62781
Saint Francis Medical CenterGrand Island, Nebraska  68802
Englewood Hospital and Medical CenterEnglewood, New Jersey  07631
New Mexico Cancer Care AssociatesSanta Fe, New Mexico  87505-7670
Mercy Health CenterOklahoma City, Oklahoma  73120
Doylestown HospitalDoylestown, Pennsylvania  18901
McLeod Regional Medical CenterFlorence, South Carolina  29501
Wellmont Holston Valley Hospital and Medical CenterKingsport, Tennessee  37662
La Grange Memorial HospitalLa Grange, Illinois  60525
Metro Health HospitalGrand Rapids, Michigan  49506
Guardian Oncology and Center for WellnessMissoula, Montana  59804
Queen's Medical CenterHonolulu, Hawaii  96813
University of VirginiaCharlottesville, Virginia  22908
University of PittsburghPittsburgh, Pennsylvania  15261
Woodwinds Health CampusWoodbury, Minnesota  55125
University of Alabama at BirminghamBirmingham, Alabama  35294-3300
Banner Baywood Medical CenterMesa, Arizona  85206
Banner Desert Medical CenterMesa, Arizona  85202
Providence HospitalMobile, Alabama  36608
Vanderbilt UniversityNashville, Tennessee  37232-6305
University of North CarolinaChapel Hill, North Carolina  27599
Duke University Medical CenterDurham, North Carolina  27710
Meharry Medical CollegeNashville, Tennessee  37208-3599
Good Samaritan Hospital of MarylandBaltimore, Maryland  21239
Providence Medical CenterKansas City, Kansas  66112
Independence Regional Health CenterIndependence, Missouri  64050
Lynchburg Hematology-Oncology ClinicLynchburg, Virginia  24501
Mercy General HospitalSacramento, California  95819
Northwestern UniversityChicago, Illinois  60611
Cancer Care AssociatesTulsa, Oklahoma  74136
Northwest Cancer SpecialistsVancouver, Washington  98664
Shore Memorial HospitalSomers Point, New Jersey  08244
East Bay Radiation Oncology CenterCastro Valley, California  94546
Contra Costa Regional Medical CenterMartinez, California  94553-3156
Memorial Medical CenterModesto, California  95355
Larry G Strieff MD Medical CorporationOakland, California  94609
Kapiolani Medical Center at Pali MomiAiea, Hawaii  96701
Kapiolani Medical Center for Women and ChildrenHonolulu, Hawaii  96826
Maui Memorial Medical CenterWailuku, Hawaii  96793
Elmhurst Memorial HospitalElmhurst, Illinois  60126
Bay Area HospitalCoos Bay, Oregon  97420
Hennepin County Medical CenterMinneapolis, Minnesota  
Queens Hospital CenterJamaica, New York  11432
Bend Memorial ClinicBend, Oregon  97701
Scripps Cancer CenterLa Jolla, California  92037
University of FloridaGainesville, Florida  32610-0277
Saint Louis University HospitalSt. Louis, Missouri  63110-0250
University of RochesterRochester, New York  14642
Saints Memorial Medical CenterLowell, Massachusetts  01852
University of ConnecticutFarmington, Connecticut  06032
Glens Falls HospitalGlens Falls, New York  12801
Saint Alphonsus Regional Medical CenterBoise, Idaho  83706
Holy Cross HospitalFort Lauderdale, Florida  33308
Cleveland Clinic Florida - WestonWeston, Florida  33331
University of California at San DiegoLa Jolla, California  92093
Case Western Reserve UniversityCleveland, Ohio  44106
High Point Regional HospitalHigh Point, North Carolina  27261
South Shore HospitalSouth Weymouth, Massachusetts  02190
Emory UniversityAtlanta, Georgia  30322
Wayne State UniversityDetroit, Michigan  48202
New Hampshire Oncology-Hematology PAHooksett, New Hampshire  03106
University of Arizona Health Sciences CenterTucson, Arizona  85724
Albert Einstein Medical CenterPhiladelphia, Pennsylvania  19141
Straub Clinic and HospitalHonolulu, Hawaii  96813
Lakeland Regional Cancer CenterLakeland, Florida  33805
University of Massachusetts Medical SchoolWorcester, Massachusetts  01605
Riverside Methodist HospitalColumbus, Ohio  43214
Licking Memorial HospitalNewark, Ohio  43055-2899
Providence Portland Medical CenterPortland, Oregon  97213-3635
California Pacific Medical CenterSan Francisco, California  94115
Dartmouth Hitchcock Medical CenterLebanon, New Hampshire  03756
Mid Dakota ClinicBismarck, North Dakota  58501
Columbus CCOPColumbus, Ohio  43206
Indiana University Medical CenterIndianapolis, Indiana  46202
Weiss Memorial HospitalChicago,, Illinois  60640
Nyack HospitalNyack, New York  10960
University Of VermontBurlington,, Vermont  05403
Presbyterian - Saint Lukes Medical Center - Health OneDenver, Colorado  80218
Sacred Heart HospitalPensacola, Florida  32503
Kaiser PermanenteSacramento, California  
University of Texas Southwestern Medical CenterDallas, Texas  
University of KentuckyLexington, Kentucky  40536-0098
Wichita CCOPWichita, Kansas  67214-3882
Montana Cancer Consortium CCOPBillings, Montana  59101
Alegent Health Immanuel Medical CenterOmaha, Nebraska  68122
Alegent Health Bergan Mercy Medical CenterOmaha, Nebraska  68124
Flower HospitalSylvania, Ohio  43560-2197
Virginia Mason CCOPSeattle, Washington  98101
Mount Sinai Hospital Medical CenterChicago, Illinois  60608
Addison Gilbert HospitalGloucester, Massachusetts  01930
Southeastern Regional Medical CenterLumberton, North Carolina  28359
Granville Medical CenterOxford, North Carolina  27565
Person Memorial HospitalRoxboro, North Carolina  27573
Columbia Saint Mary's Hospital - OzaukeeMequon, Wisconsin  53097
Providence Holy Cross Medical CenterMission Hills, California  91345
Metro-Minnesota CCOPSt. Louis Park, Minnesota  
UC Davis Comprehensive Cancer CenterSacramento, California  95817
Providence HospitalSouthfield, Michigan  48075
Lagrange Oncology AssociatesLa Grange, Illinois  60525
Virginia Cancer InstituteRichmond, Virginia  23230
Tufts Medical CenterBoston, Massachusetts  02111
Oregon Health and Science UniversityPortland, Oregon  97201
Thomas Jefferson University HospitalPhiladelphia, Pennsylvania  19131
Jersey Shore Medical CenterNeptune, New Jersey  07754
Decatur Memorial HospitalDecatur, Illinois  62526
Jackson Oncology Associates PLLCJackson, Mississippi  39202
Tulane University Health Sciences CenterNew Orleans, Louisiana  70112
Mercy Medical CenterBaltimore, Maryland  21202
Louisiana State University Health Science CenterNew Orleans, Louisiana  70112
Virginia Commonwealth UniversityRichmond, Virginia  
Kaiser PermanentePortland, Oregon  97227
Frederick Memorial HospitalFrederick, Maryland  21701
Lankenau HospitalWynnewood, Pennsylvania  19096
CentraState Medical CenterFreehold, New Jersey  07728
Ralph Lauren Center for Cancer Care and PreventionNew York, New York  10035
Princeton Community HospitalPrinceton, West Virginia  24740
Montana Cancer SpecialistsMissoula, Montana  59807-7877
Desert Regional Medical CenterPalm Springs, California  92262
Boca Raton Comprehensive Cancer CenterBoca Raton, Florida  33486
Providence Saint Joseph Medical CenterBurbank, California  91505-4866
Florida HospitalOrlando, Florida  32803
Memorial Health University Medical CenterSavannah, Georgia  31404
Hillcrest Hospital Cancer CenterMayfield Heights, Ohio  44124
Phoenixville HospitalPhoenixville, Pennsylvania  19460
University of Chicago Comprehensive Cancer CenterChicago, Illinois  60637-1470
M D Anderson Cancer CenterHouston, Texas  77030
University of Southern CaliforniaLos Angeles, California  90033
DeKalb Medical CenterDecatur, Georgia  30033
Olathe Medical CenterOlathe, Kansas  
Northern Indiana Cancer Research ConsortiumSouth Bend, Indiana  
Rockwood ClinicSpokane, Washington  99220
University of CincinnatiCincinnati, Ohio  45267-0502
Hawaii Medical Center EastHonolulu, Hawaii  96817
Vince Lombardi Cancer Clinic - OshkoshOshkosh, Wisconsin  54904
Penn State Milton S Hershey Medical CenterHershey, Pennsylvania  17033
Foundation Medical PartnersNashua, New Hampshire  03060
Hematology Oncology AssociatesAlbuquerque, New Mexico  87106
Jones ClinicGermantown, Tennessee  38138
The Community HospitalMunster, Indiana  46321
Froedtert and the Medical College of WisconsinMilwaukee, Wisconsin  53226
Mercy HospitalPortland, Maine  04101
North Broward Medical CenterDearfield Beach, Florida  33064-3596
Wake Forest University Health SciencesWinston-Salem, North Carolina  27157
OSF Saint Francis Medical CenterPeoria, Illinois  61637
Northside HospitalAtlanta, Georgia  30342
Western Regional CCOPPhoenix, Arizona  85006
Saint Edward Mercy Medical CenterFt. Smith, Arkansas  72903
Mills - Peninsula HospitalsBurlingame, California  94010
Valley Medical Oncology Consultants-Castro ValleyCastro Valley, California  94546
Eden Hospital Medical CenterCastro Valley, California  94546
Northbay Cancer CenterFairfield, California  94533
Valley Medical Oncology Consultants-FremontFremont, California  94538
Kaiser Permanente, FremontFremont, California  94538
California Cancer Center - North FresnoFresno, California  93720
Kaiser Permanente, HaywardHayward, California  94545
Fremont - Rideout Cancer CenterMarysville, California  95901
Community Hospital of Monterey PeninsulaMonterey, California  93940
Bay Area Breast Surgeons IncOakland, California  94609
Bay Area Tumor Institution CCOPOakland, California  94609
Tom K Lee IncOakland, California  94609
Kaiser Permanente-OaklandOakland, California  94611
Saint Joseph HospitalOrange, California  92868
Valley Medical Oncology ConsultantsPleasanton, California  94588
Valley Care Health System - PleasantonPleasanton, California  94588
Kaiser Permanente-Redwood CityRedwood City, California  94063
Kaiser Permanente-RichmondRichmond, California  94801
Kaiser Permanente-RosevilleRoseville, California  95661
Sutter General HospitalSacramento, California  95816
Kaiser Permanente-South SacramentoSacramento, California  95823
Kaiser Permanente - SacramentoSacramento, California  95825
Naval Medical Center -San DiegoSan Diego, California  92134
Kaiser Permanente-San FranciscoSan Francisco, California  94115
Kaiser Permanente-Santa Teresa-San JoseSan Jose, California  95119
Doctors Medical Center- JC Robinson Regional Cancer CenterSan Pablo, California  94806
Kaiser Permanente-San RafaelSan Rafael, California  94903
Santa Rosa Memorial HospitalSana Rosa, California  95405
Kaiser Permanente-Santa RosaSanta Rosa, California  95403
Kaiser Permanente-South San FranciscoSouth San Francisco, California  94080
Kaiser Permanente-StocktonStockton, California  95210
Kaiser Permanente-VallejoVallejo, California  94589
Kaiser Permanente-Walnut CreekWalnut Creek, California  94596
The Medical Center of AuroraAurora, Colorado  80012
Penrose-Saint Francis HealthcareColorado Springs, Colorado  80907
Memorial Hospital Colorado SpringsColorado Springs, Colorado  80909
Saint Anthony Central HospitalDenver, Colorado  80204
Exempla Saint Joseph HospitalDenver, Colorado  80218
Colorado Cancer Research Program CCOPDenver, Colorado  80224-2522
Saint Mary's Hospital and Regional Medical CenterGrand Junction, Colorado  81502
Saint Mary Corwin Medical CenterPueblo, Colorado  81004
Danbury HospitalDanbury, Connecticut  06810
Saint Francis Hospital and Medical CenterHartford, Connecticut  06105
Middlesex HospitalMiddletown, Connecticut  06457
The Hospital of Central ConnecticutNew Britain, Connecticut  06050
Stamford HospitalStamford, Connecticut  06904
Bayhealth Medical Center at Kent GeneralDover, Delaware  19901
Lombardi Comprehensive Cancer Center at Georgetown UniversityWashington, District of Columbia  20057
Edna Williams Cancer Center at the Baptist Cancer InstituteJacksonville, Florida  32207
The Watson ClinicLakeland, Florida  33805
Cancer Centers of Central Florida PALeesburg, Florida  34788
M D Anderson Cancer Center- OrlandoOrlando, Florida  32806
Sacred Heart Medical Oncology Group - Davis HighwayPensacola, Florida  32514
Martin Memorial Hospital - SouthStuart, Florida  34997
Martin Memorial Medical Center - NorthStuart, Florida  34994
Phoebe Putney Memorial HospitalAlbany, Georgia  31703
Atlanta Regional CCOPAtlanta, Georgia  30342
Well Star Cobb HospitalAustell, Georgia  30106
John B Amos Cancer CenterColumbus, Georgia  31904
Wellstar Kennestone HospitalMarietta, Georgia  30060
Saint Joseph's-Candler Health SystemSavannah, Georgia  31405
Oncare Hawaii Inc-POB IIHonolulu, Hawaii  96813
Oncare Hawaii Inc-KuakiniHonolulu, Hawaii  96817
University of HawaiiHonolulu, Hawaii  96813
Pacific Cancer Institute of MauiWailuku, Hawaii  96793
Saint Luke's Mountain States Tumor InstituteBoise, Idaho  83712
Saint Anthony's HealthAlton, Illinois  62002
Rush - Copley Medical CenterAurora, Illinois  60504
John H Stroger Jr Hospital of Cook CountyChicago, Illinois  60612-3785
Resurrection HealthcareChicago, Illinois  60631
Cancer Institute at Alexian BrothersElk Grove Village, Illinois  60007
Saint Francis HospitalEvanston, Illinois  60202
Evanston CCOP-NorthShore University HealthSystemEvanston, Illinois  60201
Hopedale Medical Complex - HospitalHopedale, Illinois  61747
Joliet Oncology-Hematology Associates LimitedJoliet, Illinois  60435
Midwest Center for Hematology OncologyJoliet, Illinois  60432
Provena Saint Mary's HospitalKankakee, Illinois  60901
North Shore Hematology OncologyLibertyville, Illinois  60048
Vigliotti, Antonio, P.G. M.D. (UIA Investigator)Moline, Illinois  61265
Stoffel, Thomas J MD (UIA Investigator)Moline, Illinois  61265
Garneau, Stewart C MD (UIA Investigator)Moline, Illinois  61265
Sharis, Christine M MD (UIA Investigator)Moline, Illinois  61265
Porubcin, Michael MD (UIA Investigator)Moline, Illinois  61265
Good Samaritan Regional Medical CenterMt. Vernon, Illinois  62864
Community Cancer Center FoundationNormal, Illinois  61761
Illinois CancerCare-Ottawa ClinicOttawa, Illinois  61350
Ottawa Regional Hospital and Healthcare CenterOttawa, Illinois  61350
Pekin Cancer Treatment CenterPekin, Illinois  61554
Illinois Oncology Research Association CCOPPeoria, Illinois  61615
Illinois CancerCare-PeoriaPeoria, Illinois  61615
Illinois Valley HospitalPeru, Illinois  61354
West Suburban Cancer CenterRiver Forest, Illinois  60305
Hematology Oncology Associates of Illinois - SkokieSkokie, Illinois  60076
Midwest Cancer Research Group IncorporatedSkokie, Illinois  60077
Edward H Kaplan MD and AssociatesSkokie, Illinois  60076
Saint Margaret's HospitalSpring Valley, Illinois  61362
Carle Clinic-Urbana MainUrbana, Illinois  61801
Saint Francis Hospital and Health CentersBeech Grove, Indiana  46107
Fort Wayne Medical Oncology and Hematology Inc - State BoulevardFort Wayne, Indiana  46845
Wishard HospitalIndianapolis, Indiana  46202
Saint Vincent Hospital and Health ServicesIndianapolis, Indiana  46260
Premier Oncology Hematology AssociatesMerrillville, Indiana  46410
Saint Anthony Memorial Health CenterMichigan City, Indiana  46360
Reid Hospital and Health Care ServicesRichmond, Indiana  47374
McFarland ClinicAmes, Iowa  50010
Hematology Oncology Associates-Quad CitiesBettendorf, Iowa  52722
Constantinou, Costas L MD (UIA Investigator)Bettendorf, Iowa  52722
Cedar Rapids Oncology AssociationCedar Rapids, Iowa  52403
Iowa Blood and Cancer Care PLCCedar Rapids, Iowa  52402
Mercy HospitalCedar Rapids, Iowa  52403
Saint Luke's HospitalCedar Rapids, Iowa  52402
Medical Oncology and Hematology Associates-West Des MoinesClive, Iowa  50325
Genesis Medical Center - East CampusDavenport, Iowa  52803
Iowa Oncology Research Association CCOPDes Moines, Iowa  50309
Mercy CapitolDes Moines, Iowa  50307
Mercy Medical Center - Des MoinesDes Moines, Iowa  50314
Medical Oncology and Hematology Associates-Des MoinesDes Moines, Iowa  50309
Finley HospitalDubuque, Iowa  52001
Mercy Medical Center - North IowaMason City, Iowa  50401
Mercy Medical Center-Sioux CitySioux City, Iowa  51104
Saint Luke's Regional Medical CenterSioux City, Iowa  51104
Covenant Medical CenterWaterloo, Iowa  50702
Cancer Center of Kansas - El DoradoEl Dorado, Kansas  67042
Cancer Center of Kansas-KingmanKingman, Kansas  67068
Radiation Oncology Practice Corporation SouthwestOverland Park, Kansas  66210
Cancer Center of Kansas - ParsonsParsons, Kansas  67357
Cancer Center of Kansas - PrattPratt, Kansas  67124
Stormont-Vail Regional Health CenterTopeka, Kansas  66604
Saint Francis Hospital and Medical Center - TopekaTopeka, Kansas  66606
Cancer Center of Kansas-Wichita Medical Arts TowerWichita, Kansas  67208
Cancer Center of Kansas - Main OfficeWichita, Kansas  67214
Merle Mahr Cancer CenterMadisonville, Kentucky  42431
Ochsner Clinic Foundation-Baton RougeBaton Rouge, Louisiana  70809
Metairie OncologistsMetairie, Louisiana  70006
Louisiana State University Sciences Center- MonroeMonroe, Louisiana  71210
Medical Center of LouisianaNew Orleans, Louisiana  70112
Ochsner Clinic CCOPNew Orleans, Louisiana  70121
Highland ClinicShreveport, Louisiana  71105
The Union Memorial HospitalBaltimore, Maryland  21218
Associates in Oncology Hematology PC -KensingtonKensington, Maryland  20895
Associates In Oncology Hematology PC-RockvilleRockville, Maryland  20878
Caritas Saint Elizabeth's Medical CenterBrighton, Massachusetts  02135-2997
Holy Family HospitalMethuen, Massachusetts  01844
Norwood HospitalNorwood, Massachusetts  02062
North Shore Medical Center Cancer CenterPeabody, Massachusetts  01960
Berkshire Hematology Oncology PCPittsfield, Massachusetts  01201
Commonwealth Hematology Oncology PC-QuincyQuincy, Massachusetts  02169
Morton Hospital and Medical CenterTaunton, Massachusetts  02780
Hickman Cancer CenterAdrian, Michigan  49221
Michigan Cancer Research Consortium Community Clinical Oncology ProgramAnn Arbor, Michigan  48106
Oakwood HospitalDearborn, Michigan  48123
Saint John Hospital and Medical CenterDetroit, Michigan  48236
Michigan State University - Breslin Cancer CenterEast Lansing, Michigan  48824-1313
Green Bay Oncology - EscanabaEscanaba, Michigan  49431
McLaren Regional Medical CenterFlint, Michigan  48532
Grand Rapids Clinical Oncology ProgramGrand Rapids, Michigan  49503
Saint Mary's Health CareGrand Rapids, Michigan  49503
Spectrum Health at Butterworth CampusGrand Rapids, Michigan  49503
Green Bay Oncology - Iron MountainIron Mountain, Michigan  49801
Allegiance HealthJackson, Michigan  49201
Ingham Regional Medical CenterLansing, Michigan  48910
Sparrow HospitalLansing, Michigan  48912
Saint Mary Mercy HospitalLivonia, Michigan  48154
Mid-Michigan Medical Center - MidlandMidland, Michigan  48670
Mercy Memorial HospitalMonroe, Michigan  48162
Mercy Health Partners-Mercy CampusMuskegon, Michigan  49443
Mercy Health Partners-Hackley CampusMuskegon, Michigan  49442
Northern Michigan Regional HospitalPetoskey, Michigan  49770
Saint Joseph Mercy OaklandPontiac, Michigan  48341-2985
Saint Joseph Mercy Port HuronPort Huron, Michigan  48060
Saint Mary's of MichiganSaginaw, Michigan  48601
Lakeland HospitalSt. Joseph, Michigan  49085
Saint John Macomb-Oakland HospitalWarren, Michigan  48093
Medini, Eitan MD (UIA Investigator)Alexandria, Minnesota  56308
Miller-Dwan HospitalDuluth, Minnesota  55805
Saint Luke's Hospital of DuluthDuluth, Minnesota  55805
Etzell, Paul S MD (UIA Investigator)Fergus Falls, Minnesota  56537
Swenson, Wade II, MD (UIA Investigator)Fergus Falls, Minnesota  56537
Unity HospitalFridley, Minnesota  55432
Immanuel-Saint Joseph Hospital-Mayo Health SystemMankato, Minnesota  56002
Saint John's Hospital - HealtheastMaplewood, Minnesota  55109
Minnesota Oncology Hematology PA-MaplewoodMaplewood, Minnesota  55109
North Memorial Medical Health CenterRobbinsdale, Minnesota  55422
Saint Cloud HospitalSaint Cloud, Minnesota  56303
Park Nicollet Clinic - Saint Louis ParkSaint Louis Park, Minnesota  55416
Saint Joseph's Hospital - HealtheastSaint Paul, Minnesota  55102
Minnesota Oncology and Hematology PA-WoodburyWoodbury, Minnesota  55125
Keesler Medical CenterKessler AFB, Mississippi  39534
Southeast Missouri HospitalCape Girardeau, Missouri  63701
Saint John's Regional Medical CenterJoplin, Missouri  64804
Freeman Health SystemJoplin, Missouri  64804
Radiation Oncology Practice Corporation - NorthKansas City, Missouri  64154
Saint Luke's Cancer InstituteKansas City, Missouri  64111
Radiation Oncology Practice Corporation SouthKansas City, Missouri  64114
Saint Luke's Hospital of Kansas CityKansas City, Missouri  64111
Saint Joseph Health CenterKansas City, Missouri  64114
Liberty Radiation Oncology ClinicKansas City, Missouri  64116
Truman Medical CenterKansas City, Missouri  64108
Saint Anthony's Medical CenterSaint Louis, Missouri  63128
Saint Louis-Cape Girardeau CCOPSaint Louis, Missouri  63141
Christian Hospital Northeast - NorthwestSaint Louis, Missouri  63136
Missouri Baptist Medical CenterSaint Louis, Missouri  63131
Saint John's Mercy Medical CenterSaint Louis, Missouri  63141
Ozark Health Ventures LLC dba Cancer Research for The Ozarks SpringfieldSpringfield, Missouri  65802
Saint John's HospitalSpringfield, Missouri  65804
Cox Medical CenterSpringfield, Missouri  65807
Hematology-Oncology Centers of the Northern Rockies PCBillings, Montana  59101
Saint Vincent HealthcareBillings, Montana  59101
Deaconess Medical CenterBillings, Montana  59107
Billings ClinicBillings, Montana  59107-7000
Saint James Community Hospital and Cancer Treatment CenterButte, Montana  59701
Benefis Healthcare- Sletten Cancer InstituteGreat Falls, Montana  59405
Berdeaux, Donald MD (UIA Investigator)Great Falls, Montana  59405
Saint Peter's Community HospitalHelena, Montana  59601
Glacier Oncology PLLCKalispell, Montana  59901
Community Medical HospitalMissoula, Montana  59801
Saint Patrick Hospital - Community HospitalMissoula, Montana  59802
Good Samaritan HospitalKearney, Nebraska  68847
Lincoln Medical Education Foundation Cancer Resource CenterLincoln, Nebraska  68510
Missouri Valley Cancer Consortium CCOPOmaha, Nebraska  68106
Midlands Community HospitalPapillion, Nebraska  68046
Nevada Cancer Research Foundation CCOPLas Vegas, Nevada  89106
Exeter HospitalExeter, New Hampshire  03833
New Hampshire Oncology Hematology AssociatesHooksett, New Hampshire  03106
Cheshire Medical Center-Dartmouth-Hitchcock KeeneKeene, New Hampshire  03431
LRGHealthcare-Lakes Region General HospitalLaconia, New Hampshire  03246
Elliot HospitalManchester, New Hampshire  03103
Portsmouth Regional HospitalPortsmouth, New Hampshire  03802
Ocean Medical CenterBrick, New Jersey  08724
Cooper Hospital University Medical CenterCamden, New Jersey  08103
Hunterdon Medical CenterFlemington, New Jersey  08822
Saint Barnabas Medical CenterLivingston, New Jersey  07039
Mountainside HospitalMontclair, New Jersey  07042
Fox Chase Cancer Center at Virtua Memorial Hospital of Burlington CountyMount Holly, New Jersey  08060
Sparta Cancer Treatment CenterSparta, New Jersey  07871
South Jersey HealthcareVineland, New Jersey  08360
Virtua West Jersey Hospital VoorheesVoorhees, New Jersey  08043
Presbyterian Kaseman HospitalAlbuquerque, New Mexico  87110
Adirondack Cancer CenterGlens Falls, New York  12801
Orange Regional Medical CenterMiddletown, New York  10940
New York University Langone Medical CenterNew York, New York  10016
Saint Luke's Roosevelt Hospital Center - Saint Luke's DivisionNew York, New York  10025
Columbia University Medical CenterNew York, New York  10032
Interlakes Foundation Inc-RochesterRochester, New York  14623
Highland HospitalRochester, New York  14620
State University of New York Upstate Medical UniversitySyracuse, New York  13210
Faxton-Saint Luke's HealthcareUtica, New York  13502
Mission Hospitals IncAsheville, North Carolina  28801
Gaston Memorial HospitalGastonia, North Carolina  28054
Wayne Memorial HospitalGoldsboro, North Carolina  27534
Kinston Medical Specialists PAKinston, North Carolina  28501
Marion L Shepard Cancer CenterWashington, North Carolina  27889
Saint Alexius Medical CenterBismarck, North Dakota  58501
Summa Barberton HospitalBarberton, Ohio  44203
Aultman Health FoundationCanton, Ohio  44710
Doctors HospitalColumbus, Ohio  43228
Grant Medical CenterColumbus, Ohio  43215
Mount Carmel Health Center WestColumbus, Ohio  43222
Good Samaritan Hospital - DaytonDayton, Ohio  45406
Dayton CCOPDayton, Ohio  45429
Samaritan North Health CenterDayton, Ohio  45415
Veteran Affairs Medical CenterDayton, Ohio  45428
Hematology Oncology Center IncorporatedElyria, Ohio  44035
Blanchard Valley HospitalFindlay, Ohio  45840
Atrium Medical Center-Middletown Regional HospitalFranklin, Ohio  45005-1066
Cleveland Clinic Cancer Center IndependenceIndependence, Ohio  44131
Cole, Sharon, K. M.D. (UIA Investigator)Kenton, Ohio  43326
Kettering Medical CenterKettering, Ohio  45429
Saint Rita's Medical CenterLima, Ohio  45801
Mansfield General Hospital-MedCentral Health SystemMansfield, Ohio  44903
Marietta Memorial HospitalMarietta, Ohio  45750
Toledo Radiation Oncology at Northwest Ohio Onocolgy CenterMaumee, Ohio  43537
Saint Charles HospitalOregon, Ohio  43616
North Coast Cancer CareSandusky, Ohio  44870
Toledo Community Hospital Oncology Program CCOPToledo, Ohio  43617
Mercy Cancer Center at Saint Anne Mercy HospitalToledo, Ohio  43623
University of ToledoToledo, Ohio  43614
Saint Vincent Mercy Medical CenterToledo, Ohio  43608
Upper Valley Medical CenterTroy, Ohio  45373
Saint Joseph Cancer CenterWarren, Ohio  44484
Saint Ann's HospitalWesterville, Ohio  43081
Cleveland Clinic Wooster Specialty CenterWooster, Ohio  44691
Wright-Patterson Medical CenterWright-Patterson Afb, Ohio  45433-5529
Genesis HealthCare SystemZanesville, Ohio  43701
Natalie W Bryant Cancer CenterTulsa, Oklahoma  74136
Legacy Good Samaritan Hospital and Medical CenterPortland, Oregon  97210
Northwest Cancer Specialists-Rose Quarter Cancer CenterPortland, Oregon  97227
Providence Saint Vincent Medical CenterPortland, Oregon  97225
Columbia River Oncology ProgramPortland, Oregon  97225
Salem HospitalSalem, Oregon  97309
Saint Luke's HospitalBethlehem, Pennsylvania  18015
Pocono Medical CenterEast Stroudsburg, Pennsylvania  18301
Ephrata Cancer CenterEphrata, Pennsylvania  17522
Riddle HospitalMedia, Pennsylvania  19063
Aria Health-Torresdale CampusPhiladelphia, Pennsylvania  19114
Pottstown Memorial Medical CenterPottstown, Pennsylvania  19464
Saint Joseph Medical CenterReading, Pennsylvania  19605
Hematology and Oncology Associates of North East PennsylvaniaScranton, Pennsylvania  18508
Scranton Hematology OncologyScranton, Pennsylvania  18510
Mercy HospitalScranton, Pennsylvania  18501
Associates In Hematology Oncology PC-UplandUpland, Pennsylvania  19013
Geisinger Wyoming ValleyWilkes-Barre, Pennsylvania  18711
Mainline Health CCOPWynnewood, Pennsylvania  19096
Hematology and Oncology Associates of Rhode Island IncCranston, Rhode Island  02920
Kent County HospitalWarwick, Rhode Island  02886
AnMed Health HospitalAnderson, South Carolina  29621
Greenville CCOPGreenville, South Carolina  29615
Upstate Carolina CCOPSpartanburg, South Carolina  29303
Sanford Cancer Center-Oncology ClinicSioux Falls, South Dakota  57104
Tennessee Oncology PLLC- Centennial Medical CenterNashville, Tennessee  37203
The Center for Integrative Cancer MedicineEl Paso, Texas  79902
University HospitalSan Antonio, Texas  78229
Southwestern Oncology Research DepartmentBennington, Vermont  05201
Fredericksburg Oncology IncFredericksburg, Virginia  22401
Peninsula Cancer Institute-Newport NewsNewport News, Virginia  23601
Southwest VA Regional Cancer CenterNorton, Virginia  24273
Auburn Regional Medical CenterAuburn, Washington  98002
Harrison Bremerton Hematology and OncologyBremerton, Washington  98310
Saint Francis HospitalFederal Way, Washington  98003
Columbia Basin Hematology and Oncology PLLCKennewick, Washington  99336
Evergreen Hospital Medical CenterKirkland, Washington  98033
Providence - Saint Peter HospitalOlympia, Washington  98506-5166
Good Samaritan Community HospitalPuyallup, Washington  98372
Minor and James Medical PLLCSeattle, Washington  98104
The PolyclinicSeattle, Washington  98122
Swedish Medical Center-First HillSeattle, Washington  98122-4307
Northwest CCOPTacoma, Washington  98405
Multicare Health SystemTacoma, Washington  98415
Saint Clare HospitalTacoma, Washington  98499
Saint Joseph Medical CenterTacoma, Washington  98405
Edwards Comprehensive Cancer CenterHuntington, West Virginia  25701
West Virginia UniversityMorgantown, West Virginia  26506
Wheeling HospitalWheeling, West Virginia  26003
Langlade Hospital and Cancer CenterAntigo, Wisconsin  54409
Sacred Heart HospitalEau Claire, Wisconsin  54701
Central Wisconsin Cancer ProgramFond Du Lac, Wisconsin  54935
Saint Vincent HospitalGreen Bay, Wisconsin  54301
Green Bay Oncology Limited at Saint Mary's HospitalGreen Bay, Wisconsin  54303
Saint Mary's HospitalGreen Bay, Wisconsin  54303
Green Bay Oncology at Saint Vincent HospitalGreen Bay, Wisconsin  54301-3526
Aurora BayCare Medical CenterGreen Bay, Wisconsin  54311-6519
Dean Hematology and Oncology ClinicMadison, Wisconsin  53717
Vince Lombardi Cancer Clinic-MarinetteMarinette, Wisconsin  54143
Bay Area Medical CenterMarinette, Wisconsin  54143
Marshfield Clinic-Minocqua CenterMinocqua, Wisconsin  54548
Oconomowoc Memorial Hospital-ProHealth Care IncOconomowoc, Wisconsin  53066-3896
Green Bay Oncology - Oconto FallsOconto Falls, Wisconsin  54154
Marshfield Clinic at James Beck Cancer CenterRhinelander, Wisconsin  54501
Marshfield Clinic-Rice Lake CenterRice Lake, Wisconsin  54868
Saint Michael's HospitalStevens Point, Wisconsin  54481
Green Bay Oncology - Sturgeon BaySturgeon Bay, Wisconsin  54235
Marshfield Clinic-Wausau CenterWausau, Wisconsin  54401
Aspirus Regional Cancer CenterWausau, Wisconsin  54401
University of California Medical Center At Irvine-Orange CampusOrange, California  92868
Women and Infants HospitalProvidence, Rhode Island  02905
Lynn Regional Cancer Center - WestBoca Raton, Florida  33428
Cedar Valley Medical SpecialistsWaterloo, Iowa  50702
Olathe Cancer CenterOlathe, Kansas  66061
Saint Vincent Health CenterErie, Pennsylvania  16544
Jupiter Medical CenterJupiter, Florida  33458
Rutland Regional Medical CenterRutland, Vermont  05701
University of IllinoisChicago, Illinois  60612
Stony Brook University Medical CenterStony Brook, New York  11794
Horizon Oncology CenterLafayette, Indiana  47905
York HospitalYork, Maine  03909
Cookeville Regional Medical CenterCookeville, Tennessee  38501
Lahey Clinic Medical CenterBurlington, Massachusetts  01805
Baptist Hospital EastLouisville, Kentucky  40207
Saint Michael's Medical CenterNewark, New Jersey  07102
Elkhart ClinicElkhart, Indiana  46515
John Muir Medical Center-Concord CampusConcord, California  94520
Washington HospitalFremont, California  94538
Saint Jude Medical CenterFullerton, California  92835
Marin General HospitalGreenbrae, California  94904
The Shaw Regional Cancer CenterEdwards, Colorado  81632
Montrose Memorial HospitalMontrose, Colorado  81401
Memorial Healthcare System - Joe DiMaggio Children's HospitalHollywood, Florida  33021
Mount Sinai Medical Center CCOPMiami Beach, Florida  33140
Northeast Georgia Cancer Care LLCAthens, Georgia  30607
Harbin Clinic Medical Oncology and Clinical ResearchRome, Georgia  30165
Portneuf Medical CenterPocatello, Idaho  83201
Kootenai Cancer CenterPost Falls, Idaho  83854
Illinois CancerCare-BloomingtonBloomington%, Illinois  61701
Illinois CancerCare-CantonCanton, Illinois  61520
Illinois CancerCare-CarthageCarthage, Illinois  62321
Illinois CancerCare-EurekaEureka, Illinois  61530
Illinois CancerCare-CottageGalesburg, Illinois  61401
Delnor Community HospitalGeneva, Illinois  60134
Illinois CancerCare-HavanaHavana, Illinois  62644
Illinois CancerCare-Kewanee ClinicKewanee, Illinois  61443
Illinois CancerCare-MacombMacomb, Illinois  61455
Illinois CancerCare-MonmouthMonmouth, Illinois  61462
Illinois CancerCare-Community Cancer CenterNormal, Illinois  61761
Illinois CancerCare-PekinPekin, Illinois  61603
Illinois CancerCare-PeruPeru, Illinois  61354
Illinois CancerCare-PrincetonPrinceton, Illinois  61356
Illinois CancerCare-Spring ValleySpring Valley, Illinois  61362
Michiana Hematology Oncology PC-South BendSouth Bend, Indiana  46601
Saint Mary's Regional Medical CenterLewiston, Maine  04240
Maine Medical Center- Scarborough CampusScarborough, Maine  04074
The Memorial Hospital at EastonEaston, Maryland  21601
Memorial Hospital at Easton - Shore Regional Cancer CenterEaston, Maryland  21601
Commonwealth Hematology Oncology PC-ConcordConcord, Massachusetts  01742
Commonwealth Hematology Oncology PC-HaverhillHaverhill, Massachusetts  01830
Commonwealth Hematology Oncology PC-LawrenceLawrence, Massachusetts  01842
Commonwealth Hematology Oncology PC-StonehamStoneham, Massachusetts  02180
Commonwealth Hematology Oncology PC-WeymouthWeymouth, Massachusetts  02190
Commonwealth Hematology Oncology PC-WorcesterWorcester, Massachusetts  01605
University of Michigan University HospitalAnn Arbor, Michigan  48109
University of Missouri - Ellis FischelColumbia, Missouri  65203
Veterans AdministrationColumbia, Missouri  65201
Renown Regional Medical CenterReno, Nevada  89502
John F Kennedy Medical CenterEdison, New Jersey  08818
Hackensack University Medical CCOPHackensack, New Jersey  07601
UMDNJ - New Jersey Medical SchoolNewark, New Jersey  07103
AtlantiCare Regional Medical Center -Main CampusPomona, New Jersey  08240
Carolinas Medical Center - NortheastConcord, North Carolina  28025
Moses Cone Health System-Regional Cancer CenterGreensboro, North Carolina  27403
East Carolina UniversityGreenville, North Carolina  27858
Maria Parham HospitalHenderson, North Carolina  27536
Rex Cancer CenterRaleigh, North Carolina  27607
Duke Raleigh HospitalRaleigh, North Carolina  27609
Annie Penn Memorial HospitalReidsville, North Carolina  27320
North Coast Cancer Care-ClydeClyde, Ohio  43410
Stark, Michael, Edward. M.D. (UIA Investigator)Toledo, Ohio  43623
Saint John Medical CenterTulsa, Oklahoma  74104
Oncology Hematology Associates of Northern PennsylvaniaDubois, Pennsylvania  15801
The Regional Cancer CenterErie, Pennsylvania  16505
Saint Mary Medical and Regional Cancer CenterLanghorne, Pennsylvania  19047
Chestnut Hill Health SystemPhiladelphia, Pennsylvania  19118
Roper HospitalCharleston, South Carolina  29401
Erlanger Medical CenterChattanooga, Tennessee  37403
Vanderbilt-Ingram Cancer Center Cool SpringsFranklin, Tennessee  37067
The Center for Biomedical ResearchKnoxville, Tennessee  37909
East Tennessee Baptist Hospital-Mercy Health PartnersKnoxville, Tennessee  37920
University of Tennessee - KnoxvilleKnoxville, Tennessee  37920
Nashville Oncology Associates PCNashville, Tennessee  37203
Texas Oncology-Austin NorthAustin, Texas  78759
Texas Oncology-Austin MidtownAustin, Texas  78705
Texas Oncology - Central Austin Cancer CenterAustin, Texas  78731
Texas Oncology - South Austin Cancer CenterAustin, Texas  78745
Texas Oncology-Cedar ParkCedar Park, Texas  78613
Saint Paul HospitalDallas, Texas  75235
Texas Oncology-Seton WilliamsonRound Rock, Texas  78665
Texas Oncology - Round Rock Cancer CenterRound Rock, Texas  78681
Texas Oncology- San MarcosSan Marcos, Texas  78666
Sandra L Maxwell Cancer CenterCedar City, Utah  84720
Intermountain Medical CenterMurray, Utah  84157
Utah Valley Regional Medical CenterProvo, Utah  84603
Dixie Medical Center Regional Cancer CenterSaint George, Utah  84770
Intermountain Health CareSalt Lake City, Utah  84103
Utah Cancer Specialists-Salt Lake CitySalt Lake City, Utah  84106
Southwestern Vermont Medical CenterBennington, Vermont  05201
Mount Ascutney Hospital and Health CenterWindsor, Vermont  05089
Virginia Oncology Associates-HamptonHampton, Virginia  23666
Evergreen Hematology and Oncology PSSpokane, Washington  99218
West Virginia University CharlestonCharleston, West Virginia  25304
Marshfield Clinic-Chippewa CenterChippewa Falls, Wisconsin  54729
Holy Family Memorial HospitalManitowoc, Wisconsin  54221
Wheaton Franciscan Healthcare - Saint JosephMilwaukee, Wisconsin  53210
Medical Consultants LimitedMilwaukee, Wisconsin  53215
Wheaton Franciscan Cancer Care - All SaintsRacine, Wisconsin  53405
Vince Lombardi Cancer Clinic-SheboyganSheboygan, Wisconsin  53081
Aurora Medical Center in SummitSummit, Wisconsin  53066
Vince Lombardi Cancer ClinicTwo Rivers, Wisconsin  54241
Riverview HospitalWisconsin Rapids, Wisconsin  54494
Nashville Breast CenterNashville, Tennessee  37203
Olive View-University of California Los Angeles Medical CenterSylmar, California  91342
Advocate Lutheran General HospitalPark Ridge, Illinois  60068
Monter Cancer CenterLake Success, New York  11042
Hope, A Women's Cancer CenterAsheville, North Carolina  28816
Magee-Womens Hospital - University of Pittsburgh Medical CenterPittsburgh, Pennsylvania  15213
Texas Tech University Health Sciences CenterLubbock, Texas  79430
Aurora Women's Pavilion of Aurora West Allis Medical CenterWest Allis, Wisconsin  53227
Long Beach Memorial Medical Center-Todd Cancer InstituteLong Beach, California  90806
Santa Barbara Hematology Oncology Group Inc-Santa BarbaraSanta Barbara, California  93105
Saint Vincent's Medical CenterJacksonville, Florida  32204
University of Miami Miller School of Medicine-Sylvester Cancer CenterMiami, Florida  33136
Grady Health SystemAtlanta, Georgia  30303
Christus Schumpert Saint Mary's PlaceShreveport, Louisiana  71101
University of Minnesota Medical Center-FairviewMinneapolis, Minnesota  55455
Capital Regional Medical CenterJefferson City, Missouri  65101
FirstHealth of the Carolinas-Moore Regional HosiptalPinehurst, North Carolina  28374
Waverly Hematology OncologyCary, North Carolina  27518
Cancer Centers of Southwest Oklahoma ResearchLawton, Oklahoma  
Western Maryland Health SystemCumberland, Maryland  21502
Vanderbilt Breast Center at One Hundred OaksNashville, Tennessee  37204
Saint Bernards Regional Medical CenterJonesboro, Arkansas  72401
Palchak David MDPismo Beach, California  93449
Salinas Valley MemorialSalinas, California  93901
Kaiser Permanente Medical Center-VacavilleVacaville, California  95688
Kaiser Permanente-Rock CreekLafayette, Colorado  80026
Saint Vincent's Medical CenterBridgeport, Connecticut  06606
Greenwich HospitalGreenwich, Connecticut  06830
Hinsdale Hematology Oncology Associates IncorporatedHinsdale, Illinois  60521
Saint Luke's South HospitalOverland Park, Kansas  66213
King's Daughter's Medical CenterAshland, Kentucky  41101
Owensboro Mercy Medical CenterOwensboro, Kentucky  42303
Ochsner North Shore Medical CenterCovington, Louisiana  70433
Saint Joseph Medical CenterTowson, Maryland  21204
Mount Clemens Regional Medical CenterMount Clemens, Michigan  48043
Capital Region Medical Center-Goldschmidt Cancer CenterJefferson City, Missouri  65109
Heartland Hematology and Oncology Associates IncorporatedKansas City, Missouri  64118
Saint Joseph HospitalNashua, New Hampshire  03060
The Medical Center At PrincetonPrinceton, New Jersey  08540-3298
Coney Island HospitalBrooklyn, New York  11235
Saint FrancisPoughkeepsie, New York  12601
Forsyth Memorial HospitalWinston-Salem, North Carolina  27103
The Christ HospitalCincinnati, Ohio  45219
Saint Charles Medical Center-BendBend, Oregon  97701
Asante Health SystemMedford, Oregon  97504
Rogue Valley Medical CenterMedford, Oregon  97504
Susquehanna Cancer CenterWilliamsport, Pennsylvania  17701
Saint Francis HospitalGreenville, South Carolina  29601
University of Tennessee - MemphisMemphis, Tennessee  38163
Pacific Medical Center-First HillSeattle, Washington  98104
Gundersen LutheranLa Crosse, Wisconsin  54601
Columbia Saint Mary's Water Tower Medical CommonsMilwaukee, Wisconsin  53211
Fairbanks Memorial HospitalFairbanks, Alaska  99701
Sparks Regional Medical CenterFort Smith, Arkansas  72901
Heartland Oncology and Hematology LLPCouncil Bluffs, Iowa  51503
Alegent Health Lakeside HospitalOmaha, Nebraska  68130
Carson-Tahoe Specialty Medical CenterCarson City, Nevada  89703
New York Oncology Hematology PC -Albany Medical CenterAlbany, New York  12208
New York Oncology Hematology PC - AlbanyAlbany, New York  12206
New York Oncology Hematology PC - AmsterdamAmsterdam, New York  12010
New York Oncology Hematology PC-HudsonHudson, New York  12534
New York Oncology Hematology PC - LathamLatham, New York  12110
New York Oncology Hematology PC - RexfordRexford, New York  12148
New York Oncology Hematology PC - TroyTroy, New York  12180
Oncology and Hematology Care Inc - Blue AshCincinnati, Ohio  45242
Texas Oncology Seton NorthwestAustin, Texas  78759
Dallas Oncology Consultants PADuncanville, Texas  75137
The Center for Cancer and Blood Disorders-BurlesonBurleson, Texas  76115
The Center for Cancer and Blood Disorders-CleburneCleburne, Texas  76033
The Center for Cancer and Blood Disorders-Fort WorthFort Worth, Texas  76104
The Center for Cancer and Blood Disorders-Mineral WellsMineral Wells, Texas  76067
The Center for Cancer and Blood Disorders-WeatherfordWeatherford, Texas  76086
Harold Leever Regional Cancer CenterWaterbury, Connecticut  06708
Community Regional Cancer Care-East Radiation OncologyIndianapolis, Indiana  46219
Community Regional Cancer Care-East Medical OncologyIndianapolis, Indiana  46219
Community Regional Cancer Care-NorthIndianapolis, Indiana  46256
San Francisco General HospitalSan Francisco, California  94110
Stanford University Hospitals and ClinicsStanford, California  94305
Kaiser Permanente-FranklinDenver, Colorado  80205
Beaufort Memorial HospitalBeaufort, South Carolina  29902
Siouxland Hematology Oncology AssociatesSioux City, Iowa  51101
The Schiffler Cancer Center of Wheeling HospitalWheeling, West Virginia  26003
Hattiesburg ClinicHattiesburg, Mississippi  39401
Space Coast Cancer Centers-TitusvilleTitusville, Florida  32796
The Jackson Clinic PAJackson, Tennessee  38301
Mid-Illinois Hematology Oncology AssociatesNormal, Illinois  
Saint Joseph's Regional Medical CenterPaterson, New Jersey  07503
IU Health ArnettLafayette, Indiana  
Bronx-Lebanon Hospital CenterBronx, New York  10452
Georgia Health Sciences UniversityAugusta, Georgia  30912
Jonsson Comprehensive Cancer CenterLos Angeles, California  90095
Alta Bates Summit Medical Center-Herrick CampusBerkeley, California  94704
Boca Raton Regional HospitalBoca Raton, Florida  33486
Carle Foundation - Carle Cancer CenterUrbana, Illinois  61801
Oncology Associates at Mercy Medical CenterCedar Rapids, Iowa  52403
Marie Yeager Cancer CenterSaint Joseph, Michigan  49085
Hematology Oncology Associates of Central New York PCEast Syracuse, New York  13057
Sanford Clinic North-FargoFargo, North Dakota  58102
Sanford Medical Center-FargoFargo, North Dakota  58122
Cancer Care Associates of Fresno Medical Group IncFresno, California  93720
Emory University Hospital MidtownAtlanta, Georgia  30308
Summa Akron City HospitalAkron, Ohio  44304
The Toledo Hospital/Toledo Children's HospitalToledo, Ohio  43606
Sanford USD Medical Center - Sioux FallsSioux Falls, South Dakota  57117-5134
Providence Sacred Heart Medical Center and Children's HospitalSpokane, Washington  99204
North Shore-LIJ Health System CCOPManhasset, New York  11030
Genesys Regional Medical Center-West Flint CampusFlint, Michigan  48532
Sanford Clinic North-BemidgiBemidji, Minnesota  56601
Essentia Health Duluth Clinic CCOPDuluth, Minnesota  55805
Essentia Health Saint Mary's Medical CenterDuluth, Minnesota  55805
Sanford Bismarck Medical CenterBismarck, North Dakota  58501
Toledo Clinic Cancer Centers-OregonOregon, Ohio  43616
Geisinger Medical Center-Cancer Center HazeltonHazleton, Pennsylvania  18201
Veterans Administration-San Diego Medical CenterSan Diego, California  92161
Presbyterian Intercommunity HospitalWhittier, California  90602
Community Howard Regional HealthKokomo, Indiana  46904
Indiana University Health La Porte HospitalLa Porte, Indiana  46350
Saint Joseph Regional Medical Center-MishawakaMishawaka, Indiana  46545-1470
Moorehead Memorial HospitalEden, North Carolina  27288
PeaceHealth Saint Joseph Medical CenterBellingham, Washington  98225
Aurora Cancer Care-FranklinFranklin, Wisconsin  53132
Aurora Cancer Care-GlendaleGlendale, Wisconsin  53212
Aurora Cancer Care-Kenosha SouthKenosha, Wisconsin  53142
Aurora Cancer Care-Milwaukee SouthMilwaukee, Wisconsin  53215
Aurora Cancer Care-Milwaukee WestWauwatosa, Wisconsin  53226
Christiana Care Health System-Christiana HospitalNewark, Delaware  19718
Illinois Cancer Specialists-NilesNiles, Illinois  60714
Bronson Battle CreekBattle Creek, Michigan  49017
Riverview Medical Center/Booker Cancer CenterRed Bank, New Jersey  07701
Springfield Regional Medical CenterSpringfield, Ohio  45505
Cleveland Clinic Cancer Center/Fairview HospitalCleveland, Ohio  44111
Cancer Specialists of North Florida-Orange ParkOrange Park, Florida  32073
The James Graham Brown Cancer Center at University of LouisvilleLouisville, Kentucky  40202
NEA Baptist Memorial HospitalJonesboro, Arkansas  72401
Augusta Oncology Associates PC-Saint SebastianAugusta, Georgia  30901
Edward Hospital/Cancer CenterNaperville, Illinois  60540
Lake Region Healthcare Corporation-Cancer CareFergus Falls, Minnesota  56537
Saint Louis Cancer and Breast Institute-South CitySaint Louis, Missouri  63109
Toledo Clinic Cancer Centers-Bowling GreenBowling Green, Ohio  43402
Toledo Clinic Cancer Centers-MaumeeMaumee, Ohio  43537-1839
Toledo Clinic Cancer Centers-ToledoToledo, Ohio  43623
PinnacleHealth Fox Chase Regional Cancer Center at Polyclinic HospitalHarrisburg, Pennsylvania  17110
Guthrie Clinic-Robert Packer HospitalSayre, Pennsylvania  18840
Harrison Poulsbo Hematology and OncologyPoulsbo, Washington  98370
Providence Holy Family HospitalSpokane, Washington  99208
PeaceHealth Southwest Medical CenterVancouver, Washington  98664
Aurora Cancer Care-Southern LakesElkhorn, Wisconsin  53121
Mayo Clinic Health System-Franciscan HealthcareLa Crosse, Wisconsin  54601
Simonds-Sinon Regional Cancer CenterFitchburg, Massachusetts  01420
Mercy Regional Cancer CenterRedding, California  96001
Ray, Margaret, Savage. M.D. (UIA Investigator)Santa Barbara, California  93111
Sansum Clinic IncSanta Barbara, California  93105
Santa Barbara Hematology Oncology Group Inc-SolvangSolvang, California  93463
Emanuel Medical CenterTurlock, California  95382
Halifax Health Medical Center-Centers for OncologyDaytona Beach, Florida  32114
Indiana University Health BloomingtonBloomington, Indiana  47403
Medical Associates Clinic PCDubuque, Iowa  52001
Christus Saint Frances Cabrini HospitalAlexandria, Louisiana  71301
Overton Brooks Veteran's Administration Medical CenterShreveport, Louisiana  71101
Maine Center for Cancer Medicine and Blood Disorders-ScarboroughScarborough, Maine  04074
Commonwealth Hematology Oncology PC-DorchesterDorchester, Massachusetts  02124
HealthAlliance Hospital - LeominsterLeominster, Massachusetts  01453
Crittenton HospitalRochester, Michigan  48307
San Juan Regional Medical CenterSan Juan, New Mexico  87401
Saint Vincent's Hospital and Medical Center of New YorkNew York, New York  10011
Hudson Valley Hematology Oncology AssociatesPoughkeepsie, New York  12601
The Dyson Center for Cancer CarePoughkeepsie, New York  12601
Park Ridge Hospital Breast Health CenterHendersonville, North Carolina  28792
Community Hospital and Wellness CentersBryan, Ohio  43506
Holy Redeemer Hospital and Medical CenterMeadowbrook, Pennsylvania  19046
South Carolina Oncology Associates PAColumbia, South Carolina  29210
Blue Ridge Medical Specialists PCBristol, Tennessee  37620
Saint Joseph Regional Cancer CenterBryan, Texas  77802
Covenant Medical Center-LakesideLubbock, Texas  79410
Peninsula Cancer Center-GloucesterGloucester, Virginia  23061
Sentara Surgery Specialists-JeffersonNewport News, Virginia  23606
Peninsula Cancer Institute-WilliamsburgWilliamsburg, Virginia  23185
Fox Valley Surgical Associates LimitedAppleton, Wisconsin  54911
Columbia Saint Mary's Hospital -MilwaukeeMilwaukee, Wisconsin  53211