Smoking Relapse Prevention Among Postpartum Women
- Develop and evaluate 2 "Motivational Relapse Prevention" (MRP) treatments of varying
intensity for reducing postpartum smoking relapse among pregnant women who quit smoking
- Assess MRP and Enhanced MRP (MRP+) effects on treatment mechanisms and the role of
those mechanisms in mediating MRP and MRP+ effects on abstinence.
- Assess the cost-effectiveness of both the MRP and MRP+ treatments relative to each
other and to usual care for reducing postpartum smoking relapse.
OUTLINE: This is a randomized study. Participants are randomized to 1 of 3 intervention
- Arm I (usual care [UC]): Participants receive self-help materials and brief relapse
prevention advice based on the Treating Tobacco Use and Dependence Clinical Practice
- Arm II (motivational relapse prevention [MRP]): Participants receive the same
intervention as in arm I. Participants also undergo telephone counseling over 30
minutes at 34 and 36 weeks gestation and then at 2, 4, 7, and 16 weeks postpartum.
- Arm III (enhanced MRP [MRP+]): Participants receive the same intervention as in arm I
and telephone counseling as in arm II. Participants also undergo in-person counseling
over 1 hour at 30-33 weeks gestation and then at 8 weeks postpartum.
Participants in all arms complete questionnaires at baseline, at 30-33 weeks gestation, and
then at 8 and 26 weeks postpartum.
Participants are followed at 8 and 26 weeks postpartum.
PROJECTED ACCRUAL: A total of 450 participants will be accrued for this study.
Observational Model: Case-Only, Time Perspective: Prospective
Number of Patients with Smoking Abstinence
Smoking abstinence as measured by the Society for Research on Nicotine and Tobacco Smoking Status Measure at 26 weeks following study treatment
David Wetter, PhD, BS, BA
M.D. Anderson Cancer Center
United States: Institutional Review Board
|M. D. Anderson Cancer Center at University of Texas||Houston, Texas 77030-4009|