A Survey of Disease and Treatment-Related Symptoms in Patients With Invasive Cancer: Prevalence, Severity and Treatment
- Determine the prevalence, severity, and interference due to physical and psychological
symptoms experienced (over a 4 to 5 week period) by patients with invasive primary
breast, lung, prostate, or colorectal cancer who are being followed on an outpatient
basis at ECOG institutions.
- Determine if the number of symptom-related interventions are related to the providers'
perception of symptom severity.
- Determine whether physical symptoms are more commonly prioritized and treated compared
to psychological symptoms.
- Determine the percentage of patients who experience a significant reduction in
moderate-to-severe symptoms and characterize the determinants of symptom relief.
- Determine the focus and scope of interventions chosen by oncologists to improve the
symptom control of patients seen in outpatient clinics.
OUTLINE: This is an open-label, multicenter study. Patients are stratified according to
disease type, prevalence according to gender, race/ethnicity, age, and type of treatment.
Patients complete the M.D. Anderson Symptom Assessment Inventory and other questionnaires,
rating the symptoms most frequently found in this patient group and how much these symptoms
interfere with mood and activity-related domains, on day 1 and again between days 28-35.
At the same time points, a healthcare provider (treating physician, nurse, or physician
assistant) completes the Revised Edmonton Staging System for Cancer Pain questionnaire,
assessing the patient's cancer pain on the basis of mechanism of pain, incidental pain,
psychological distress and addictive behavior, and cognitive function, for clinical
prognosis on pain control.
PROJECTED ACCRUAL: A total of 2,310 patients and their physicians will be accrued for this
Prevalence, severity, and interference due to physical and psychological symptoms experienced by cancer patients as assessed by MD Anderson Symptom Inventory at baseline and days 28-35 following initial assessment
Michael J. Fisch, MD, MPH, FACP
M.D. Anderson Cancer Center
United States: Federal Government
|Hurley Medical Center||Flint, Michigan 48503|
|Mercy Medical Center - Sioux City||Sioux City, Iowa 51104|
|Siouxland Hematology-Oncology Associates, LLP||Sioux City, Iowa 51101|
|St. Luke's Regional Medical Center||Sioux City, Iowa 51104|
|CCOP - Michigan Cancer Research Consortium||Ann Arbor, Michigan 48106|
|Saint Joseph Mercy Cancer Center||Ann Arbor, Michigan 48106-0995|
|Oakwood Cancer Center at Oakwood Hospital and Medical Center||Dearborn, Michigan 48123-2500|
|Genesys Hurley Cancer Institute||Flint, Michigan 48503|
|Van Elslander Cancer Center at St. John Hospital and Medical Center||Grosse Pointe Woods, Michigan 48236|
|Sparrow Regional Cancer Center||Lansing, Michigan 48912-1811|
|St. John Macomb Hospital||Warren, Michigan 48093|
|Sanford Cancer Center at Sanford USD Medical Center||Sioux Falls, South Dakota 57117-5039|
|Medical X-Ray Center, PC||Sioux Falls, South Dakota 57105|
|Avera Cancer Institute||Sioux Falls, South Dakota 57105|
|Memorial Hospital of South Bend||South Bend, Indiana 46601|
|CCOP - Northern Indiana CR Consortium||South Bend, Indiana 46601|
|Saint Joseph Regional Medical Center||South Bend, Indiana 46617|
|Robert H. Lurie Comprehensive Cancer Center at Northwestern University||Chicago, Illinois 60611|
|Elkhart General Hospital||Elkhart, Indiana 46515|
|Howard Community Hospital||Kokomo, Indiana 46904|
|South Bend Clinic||South Bend, Indiana 46617|
|Lakeland Regional Cancer Care Center - St. Joseph||St. Joseph, Michigan 49085|
|Center for Cancer Therapy at LaPorte Hospital and Health Services||La Porte, Indiana 46350|
|Mercy Cancer Center at Mercy Medical Center - North Iowa||Mason City, Iowa 50401|
|Evanston Hospital||Evanston, Illinois 60201-1781|
|McFarland Clinic, PC||Ames, Iowa 50010|
|Foote Memorial Hospital||Jackson, Michigan 49201|
|St. Mary Mercy Hospital||Livonia, Michigan 48154|
|St. Joseph Mercy Oakland||Pontiac, Michigan 48341-2985|
|Mercy Regional Cancer Center at Mercy Hospital||Port Huron, Michigan 48060|
|Seton Cancer Institute at Saint Mary's - Saginaw||Saginaw, Michigan 48601|
|John H. Stroger, Jr. Hospital of Cook County||Chicago, Illinois 60612-9985|