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Phase 4
18 Years
65 Years
Not Enrolling
Both
Chemotherapy-Induced Cardiotoxicity Revealed by TnI Increase.

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Trial Information


Inclusion Criteria:



- Consecutive patients undergoing high-dose chemotherapy showing early release of
Troponin I

Exclusion Criteria:

- Contraindication to ACE-inhibitors

- On-going therapy with beta-blockers, ACE-inhibitors, angiotensin-receptors blockers

Type of Study:

Interventional

Study Design:

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind, Primary Purpose: Prevention

Outcome Measure:

Incidence of chemotherapy-induced cardiotoxicity

Principal Investigator

Carlo M Cipolla, MD

Investigator Role:

Study Director

Investigator Affiliation:

European Institute of Oncology

Authority:

Italy: Ministry of Health

Study ID:

IEO S67/500

NCT ID:

NCT00292526

Start Date:

Completion Date:

Related Keywords:

  • Chemotherapy-Induced Cardiotoxicity Revealed by TnI Increase.
  • Chemotherapy-induced cardiotoxicity
  • Troponin
  • Heart failure

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