Inclusion Criteria

Inclusion criteria:

- A female subject between, and including, 10 and 14 years of age at the time of the
first vaccination.

- Written informed assent from the subject and informed consent from the parent or
guardian of the subject should be obtained prior to enrolment.

- Subjects must have a negative urine pregnancy test.

- Healthy subject before entering the study as established by medical history and
clinical examination.

- Subject must be of non-childbearing potential.

Exclusion criteria:

- Pregnant or breastfeeding.

- Previous vaccination against HPV.

- Known acute or chronic, clinically significant neurologic, hepatic or renal
functional abnormality

- History of chronic condition(s) requiring treatment such as cancer, chronic hepatic
or kidney disease(s), diabetes, or autoimmune disease."