Presbyopia in Breast Cancer Survivors
Chemotherapy drugs, used in cancer treatments, may change the timing of a vision condition
known as presbyopia. Presbyopia is the inability to focus the eye on close objects, by a
process called accommodation. It is caused by an increase in the stiffness of the lens of
the eye that occurs naturally with aging. Currently, there are no known treatments that can
be used to prevent or delay presbyopia. As a result, the risk, in later life, of having
this condition is essentially 100%.
The purpose of this research is to determine whether chemotherapy drugs are delaying the age
at which people develop symptoms of presbyopia. We hope to establish that presbyopia can in
fact be delayed with the use of drugs, which would ultimately lead to further research in
this area.
Observational
Time Perspective: Retrospective
John Mackey, Dr.
Principal Investigator
Alberta Health Services
Canada: Health Canada
BR-1-0072
NCT00271661
August 2005
May 2006
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